{"id":7688,"date":"2024-04-26T15:25:55","date_gmt":"2024-04-26T07:25:55","guid":{"rendered":"https:\/\/www.efbiotech.com\/wordpress\/?page_id=7688"},"modified":"2024-06-02T16:33:02","modified_gmt":"2024-06-02T08:33:02","slug":"facing-challenges-in-brain-cancer-treatment","status":"publish","type":"page","link":"https:\/\/www.efbiotech.com\/wordpress\/?page_id=7688","title":{"rendered":"Facing Challenges in Brain Cancer Treatment"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"7688\" class=\"elementor elementor-7688\">\n\t\t\t\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-577d1545 elementor-section-full_width elementor-section-stretched elementor-hidden-mobile elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"577d1545\" data-element_type=\"section\" data-settings=\"{&quot;stretch_section&quot;:&quot;section-stretched&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-480852de\" data-id=\"480852de\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-3fa4aa99 elementor-widget elementor-widget-image\" data-id=\"3fa4aa99\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.11.5 - 14-03-2023 *\/\n.elementor-widget-image{text-align:center}.elementor-widget-image a{display:inline-block}.elementor-widget-image a img[src$=\".svg\"]{width:48px}.elementor-widget-image img{vertical-align:middle;display:inline-block}<\/style>\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"1366\" height=\"456\" src=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2024\/04\/challenge-for-treating-brain-tumours.png\" class=\"attachment-full size-full wp-image-7650\" alt=\"\" srcset=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2024\/04\/challenge-for-treating-brain-tumours.png 1366w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2024\/04\/challenge-for-treating-brain-tumours-300x100.png 300w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2024\/04\/challenge-for-treating-brain-tumours-1024x342.png 1024w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2024\/04\/challenge-for-treating-brain-tumours-768x256.png 768w\" sizes=\"(max-width: 1366px) 100vw, 1366px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-171aeb60 elementor-widget elementor-widget-spacer\" data-id=\"171aeb60\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.11.5 - 14-03-2023 *\/\n.elementor-column .elementor-spacer-inner{height:var(--spacer-size)}.e-con{--container-widget-width:100%}.e-con-inner>.elementor-widget-spacer,.e-con>.elementor-widget-spacer{width:var(--container-widget-width,var(--spacer-size));--align-self:var(--container-widget-align-self,initial);--flex-shrink:0}.e-con-inner>.elementor-widget-spacer>.elementor-widget-container,.e-con-inner>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer,.e-con>.elementor-widget-spacer>.elementor-widget-container,.e-con>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer{height:100%}.e-con-inner>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer>.elementor-spacer-inner,.e-con>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer>.elementor-spacer-inner{height:var(--container-widget-height,var(--spacer-size))}<\/style>\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-485743f5 elementor-section-full_width elementor-section-stretched elementor-hidden-desktop elementor-hidden-tablet elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"485743f5\" data-element_type=\"section\" data-settings=\"{&quot;stretch_section&quot;:&quot;section-stretched&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-5b773f48\" data-id=\"5b773f48\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-38474c1 elementor-widget-mobile__width-inherit elementor-widget elementor-widget-image\" data-id=\"38474c1\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"1080\" height=\"1080\" src=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2024\/04\/challenge-for-treating-brain-tumours-phone.png\" class=\"attachment-full size-full wp-image-7651\" alt=\"\" srcset=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2024\/04\/challenge-for-treating-brain-tumours-phone.png 1080w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2024\/04\/challenge-for-treating-brain-tumours-phone-300x300.png 300w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2024\/04\/challenge-for-treating-brain-tumours-phone-1024x1024.png 1024w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2024\/04\/challenge-for-treating-brain-tumours-phone-150x150.png 150w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2024\/04\/challenge-for-treating-brain-tumours-phone-768x768.png 768w\" sizes=\"(max-width: 1080px) 100vw, 1080px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2bfc5b59 elementor-widget elementor-widget-spacer\" data-id=\"2bfc5b59\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-7da6a122 elementor-section-stretched elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"7da6a122\" data-element_type=\"section\" data-settings=\"{&quot;stretch_section&quot;:&quot;section-stretched&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-79a0356a\" data-id=\"79a0356a\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-1ed95c08 elementor-widget elementor-widget-heading\" data-id=\"1ed95c08\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.11.5 - 14-03-2023 *\/\n.elementor-heading-title{padding:0;margin:0;line-height:1}.elementor-widget-heading .elementor-heading-title[class*=elementor-size-]>a{color:inherit;font-size:inherit;line-height:inherit}.elementor-widget-heading .elementor-heading-title.elementor-size-small{font-size:15px}.elementor-widget-heading .elementor-heading-title.elementor-size-medium{font-size:19px}.elementor-widget-heading .elementor-heading-title.elementor-size-large{font-size:29px}.elementor-widget-heading .elementor-heading-title.elementor-size-xl{font-size:39px}.elementor-widget-heading .elementor-heading-title.elementor-size-xxl{font-size:59px}<\/style><h1 class=\"elementor-heading-title elementor-size-medium\">Facing Challenges in Brain Cancer Treatment<\/h1>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-7d0aacae elementor-widget elementor-widget-text-editor\" data-id=\"7d0aacae\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.11.5 - 14-03-2023 *\/\n.elementor-widget-text-editor.elementor-drop-cap-view-stacked .elementor-drop-cap{background-color:#818a91;color:#fff}.elementor-widget-text-editor.elementor-drop-cap-view-framed .elementor-drop-cap{color:#818a91;border:3px solid;background-color:transparent}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap{margin-top:8px}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap-letter{width:1em;height:1em}.elementor-widget-text-editor .elementor-drop-cap{float:left;text-align:center;line-height:1;font-size:50px}.elementor-widget-text-editor .elementor-drop-cap-letter{display:inline-block}<\/style>\t\t\t\t<p style=\"text-align: center;\"><strong>Treating glioblastoma multiforme (GBM), a particularly challenging form of brain cancer, presents numerous obstacles. <\/strong><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-6e5c2bec elementor-widget elementor-widget-text-editor\" data-id=\"6e5c2bec\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><span style=\"color: #0d344a;\"><a href=\"https:\/\/www.efbiotech.com\/wordpress\/?page_id=1778\">GBM treatment<\/a> is fraught with difficulties due to the tumor&#8217;s deep-seated location within the brain and its protection by the <a href=\"https:\/\/www.efbiotech.com\/wordpress\/?page_id=6277\">blood-brain barrier<\/a>. This barrier impedes the effective delivery of chemotherapy drugs to the tumor site. Additionally, the indistinct margins of the tumor <a href=\"https:\/\/www.efbiotech.com\/wordpress\/?page_id=7850\">make complete surgical resection challenging<\/a>. Clinical evidence suggests that maximal tumor resection significantly improves patient survival.<\/span><\/p><p><span style=\"color: #0d344a;\">Moreover, residual tumor cells and cancer stem cells may continue to proliferate, leading to an increased rate of GBM recurrence. The regenerative microenvironment following <a href=\"https:\/\/www.efbiotech.com\/wordpress\/?page_id=7850\">tumor resection<\/a> further enhances the malignancy of remaining brain cancer cells, while tumor heterogeneity limits the efficacy of single-target therapies. Cancer stem cells, rapid proliferation, and recurrence contribute to disease progression. Furthermore, chemotherapy resistance and immune suppression undermine conventional treatments, including chemotherapy and immunotherapy, while current chemotherapy drugs often induce neurological side effects and increase the burden on caregivers. These factors collectively pose significant challenges to the prognosis of brain cancer patients.<\/span><\/p><p><span style=\"color: #0d344a;\"><b>For further insights into glioblastoma multiforme (GBM) \ud83d\udc49<a href=\"https:\/\/www.efbiotech.com\/wordpress\/?page_id=5824\">read more<\/a><\/b><\/span><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-37b809bc elementor-widget elementor-widget-spacer\" data-id=\"37b809bc\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-7e1c86c7 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"7e1c86c7\" data-element_type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.11.5 - 14-03-2023 *\/\n.elementor-widget-divider{--divider-border-style:none;--divider-border-width:1px;--divider-color:#2c2c2c;--divider-icon-size:20px;--divider-element-spacing:10px;--divider-pattern-height:24px;--divider-pattern-size:20px;--divider-pattern-url:none;--divider-pattern-repeat:repeat-x}.elementor-widget-divider .elementor-divider{display:flex}.elementor-widget-divider .elementor-divider__text{font-size:15px;line-height:1;max-width:95%}.elementor-widget-divider .elementor-divider__element{margin:0 var(--divider-element-spacing);flex-shrink:0}.elementor-widget-divider .elementor-icon{font-size:var(--divider-icon-size)}.elementor-widget-divider .elementor-divider-separator{display:flex;margin:0;direction:ltr}.elementor-widget-divider--view-line_icon .elementor-divider-separator,.elementor-widget-divider--view-line_text 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.elementor-divider-separator:before,.elementor-widget-divider--separator-type-pattern:not([class*=elementor-widget-divider--view]) .elementor-divider-separator{width:100%;min-height:var(--divider-pattern-height);-webkit-mask-size:var(--divider-pattern-size) 100%;mask-size:var(--divider-pattern-size) 100%;-webkit-mask-repeat:var(--divider-pattern-repeat);mask-repeat:var(--divider-pattern-repeat);background-color:var(--divider-color);-webkit-mask-image:var(--divider-pattern-url);mask-image:var(--divider-pattern-url)}.elementor-widget-divider--no-spacing{--divider-pattern-size:auto}.elementor-widget-divider--bg-round{--divider-pattern-repeat:round}.rtl .elementor-widget-divider .elementor-divider__text{direction:rtl}.e-con-inner>.elementor-widget-divider,.e-con>.elementor-widget-divider{width:var(--container-widget-width,100%);--flex-grow:var(--container-widget-flex-grow)}<\/style>\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4c6fe53f elementor-widget elementor-widget-spacer\" data-id=\"4c6fe53f\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-6fcff198 elementor-widget elementor-widget-heading\" data-id=\"6fcff198\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-medium\">Background of GBM<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-46459208 elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"46459208\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-inner-column elementor-element elementor-element-16006245\" data-id=\"16006245\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-47a68a5d elementor-widget elementor-widget-image\" data-id=\"47a68a5d\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"400\" height=\"400\" src=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2024\/04\/\u95dc\u65bcGBM.png\" class=\"attachment-full size-full wp-image-7653\" alt=\"\" srcset=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2024\/04\/\u95dc\u65bcGBM.png 400w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2024\/04\/\u95dc\u65bcGBM-300x300.png 300w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2024\/04\/\u95dc\u65bcGBM-150x150.png 150w\" sizes=\"(max-width: 400px) 100vw, 400px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-66 elementor-inner-column elementor-element elementor-element-57b6c706\" data-id=\"57b6c706\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-f52e769 elementor-widget elementor-widget-text-editor\" data-id=\"f52e769\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<ul>\n<li><span style=\"color: #0d344a;\"><strong>Lack of effective treatment:<\/strong> According to statistics from the American Cancer Society (ACS) and the Central Brain Tumor Registry of the United States (CBTRUS), an estimated 20,000 new brain tumor cases are diagnosed each year, with approximately 400 new cases of malignant gliomas in Taiwan annually. The current conventional therapies for treating malignant brain tumors, including surgical treatment, radiation therapy, and chemotherapy, have very limited efficacy.&nbsp;<\/span><span style=\"color: rgb(13, 52, 74); font-family: Arial, sans-serif; font-size: 14px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400;\">Furthermore, due to the protection of the&nbsp;<\/span><a href=\"https:\/\/www.efbiotech.com\/wordpress\/?page_id=6277\" style=\"font-variant-ligatures: normal; font-variant-caps: normal; font-family: Arial, sans-serif; font-size: 14px; font-style: normal; font-weight: 400;\">blood-brain barrier<\/a><span style=\"color: rgb(13, 52, 74); font-family: Arial, sans-serif; font-size: 14px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400;\">&nbsp;in the affected area, there are currently no truly curative drugs available, necessitating the development of new-generation therapies.<\/span><\/li>\n<\/ul>\n<ul>\n<li><span style=\"color: #0d344a;\"><strong>Rapid recurrence and low survival rates:<\/strong> <a href=\"https:\/\/www.efbiotech.com\/wordpress\/?page_id=5824\">Glioblastoma Multiforme<\/a> (GBM) can grow up to 16 times its size within one month and is a rapidly worsening primary brain tumor. The recurrence rate after surgery is also very high, often requiring patients to repeatedly undergo hospital treatments. Patients diagnosed with stage IV GBM have an average survival time of only 12 to 18 months. Malignant brain tumors spread rapidly and are challenging to eradicate. Once diagnosed, they are usually in advanced stages, and the average survival period is often around one year, with a 5-year survival rate of only 3.4%. The current standard treatment for malignant brain tumors involves a combination of surgery, radiation therapy, and chemotherapy, all of which have limited effectiveness.<\/span><\/li>\n<li><span style=\"color: #0d344a;\"><strong>Several celebrities have encountered this unfortunate condition:<\/strong> Prominent individuals both domestically and internationally have died from incurable GBM, including U.S. Senators John Sidney McCain and Edward M. Kennedy, British politician Tessa Jowell, and New York Times journalist Tom Wicker.<\/span><\/li>\n<li><span style=\"color: #0d344a;\"><strong>Diagnosis:<\/strong> The most common early symptom of brain tumors is headaches. Clinical symptoms may include headaches, increased intracranial pressure, double vision, and difficulty articulating thoughts, all of which may indicate a possible brain tumor. These symptoms are usually due to the tumor&#8217;s growth causing compression and edema in the brain tissues. Therefore, it is essential to be vigilant about any unusual bodily changes. If the above symptoms occur and worsen progressively, they may be related to GBM, making early detection challenging. In 2018, a woman named Mrs. Guo from Tzu Chi Hospital was diagnosed with GBM after experiencing sudden paralysis and collapsing due to dizziness.<\/span><\/li>\n<\/ul>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<div class=\"elementor-element elementor-element-3c671e52 elementor-widget elementor-widget-spacer\" data-id=\"3c671e52\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-208e497d elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"208e497d\" data-element_type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3e4cb2a9 elementor-widget elementor-widget-heading\" data-id=\"3e4cb2a9\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-medium\">Challenges in Brain Cancer Treatment<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-20940257 elementor-widget elementor-widget-spacer\" data-id=\"20940257\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-74697c70 elementor-section-height-min-height elementor-section-boxed elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"74697c70\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-narrow\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-50998cc9\" data-id=\"50998cc9\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-31029c5a elementor-widget elementor-widget-image\" data-id=\"31029c5a\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"150\" height=\"150\" src=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2024\/04\/\u8166\u624b\u8853-150x150.png\" class=\"attachment-thumbnail size-thumbnail wp-image-7652\" alt=\"\" srcset=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2024\/04\/\u8166\u624b\u8853-150x150.png 150w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2024\/04\/\u8166\u624b\u8853-300x300.png 300w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2024\/04\/\u8166\u624b\u8853.png 400w\" sizes=\"(max-width: 150px) 100vw, 150px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-2357a2e9\" data-id=\"2357a2e9\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-570f076e elementor-widget elementor-widget-text-editor\" data-id=\"570f076e\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<h6><span style=\"color: #0d344a;\"><b>Brain Tumor Location<\/b><\/span><\/h6><ul><li><span style=\"color: #0d344a;\"><strong>Protected by the Scalp and Skull:<\/strong> Malignant brain tumors are typically located in areas that even the most skilled neurosurgeons cannot access without penetrating the scalp and skull during surgery.\u00a0<\/span><\/li><li><span style=\"color: #0d344a;\"><b>Ill-defined Margins &#8211; Difficult to Completely Remove Tumors:<\/b> The indistinct margins of tumors make it challenging for neurosurgeons to achieve complete resection. Additionally, tumors may be located close to brain regions with similar physiological functions, further complicating the task of maximizing tumor removal, posing a significant challenge for physicians.<\/span><\/li><\/ul>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-11f4d65c elementor-section-height-min-height elementor-section-boxed elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"11f4d65c\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-narrow\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-4c96a887\" data-id=\"4c96a887\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-47b761a6 elementor-widget elementor-widget-image\" data-id=\"47b761a6\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"150\" height=\"150\" src=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2024\/04\/\u8840\u8166\u5c4f\u969c-150x150.png\" class=\"attachment-thumbnail size-thumbnail wp-image-7654\" alt=\"\" srcset=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2024\/04\/\u8840\u8166\u5c4f\u969c-150x150.png 150w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2024\/04\/\u8840\u8166\u5c4f\u969c-300x300.png 300w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2024\/04\/\u8840\u8166\u5c4f\u969c.png 400w\" sizes=\"(max-width: 150px) 100vw, 150px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-17a65720\" data-id=\"17a65720\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-3830f1d3 elementor-widget elementor-widget-text-editor\" data-id=\"3830f1d3\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<h6><span style=\"color: #0d344a;\"><b>Blood-brain barrier<\/b><\/span><\/h6><ul><li><span style=\"color: #0d344a;\">The <b>Blood-Brain Barrier (BBB)<\/b> is a highly specialized barrier that separates the bloodstream from the central nervous system (CNS), consisting of the brain&#8217;s blood vessels and the CNS. Composed of specialized endothelial cells that cover the brain capillaries, the BBB regulates the passage of substances between the bloodstream and the brain. Its structure and function depend on complex interactions between different cell types, such as endothelial cells, astrocytes, and pericytes, as well as the extracellular matrix in the capillaries. These cells are tightly arranged, preventing most substances from entering the brain tissue. The BBB&#8217;s role is to protect the brain from toxins, bacteria, viruses, and other harmful substances present in the blood, while also regulating the transport of essential molecules and maintaining a stable environment. However, this barrier also poses a challenge in treating diseases of the CNS, as it restricts the passage of therapeutic agents, including chemotherapy drugs, to the site of the disease. Therefore, overcoming the BBB is a significant challenge in brain cancer treatment.<\/span><\/li><\/ul><p><b><span style=\"color: #0d344a;\">M<span style=\"font-family: Arial, sans-serif; font-size: 14px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal;\">ore information about\u00a0<\/span><span style=\"font-family: Arial, sans-serif; font-size: 14px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal;\">Blood-Brain Barrier (BBB)\u00a0<\/span><\/span><span style=\"font-family: Arial, sans-serif; font-size: 14px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal;\"><span style=\"color: #0d344a;\">\ud83d\udc49<a href=\"https:\/\/www.efbiotech.com\/wordpress\/?page_id=6277\">read more<\/a><\/span><\/span><\/b><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-56d7f140 elementor-section-height-min-height elementor-section-boxed elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"56d7f140\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-narrow\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-20d28035\" data-id=\"20d28035\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-11ea5751 elementor-widget elementor-widget-image\" data-id=\"11ea5751\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"150\" height=\"150\" src=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2024\/04\/\u8166\u816b\u7624\u7d30\u80de\u5206\u6790-150x150.png\" class=\"attachment-thumbnail size-thumbnail wp-image-7655\" alt=\"\" srcset=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2024\/04\/\u8166\u816b\u7624\u7d30\u80de\u5206\u6790-150x150.png 150w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2024\/04\/\u8166\u816b\u7624\u7d30\u80de\u5206\u6790-300x300.png 300w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2024\/04\/\u8166\u816b\u7624\u7d30\u80de\u5206\u6790.png 400w\" sizes=\"(max-width: 150px) 100vw, 150px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-4e46f37e\" data-id=\"4e46f37e\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-5173bb0c elementor-widget elementor-widget-text-editor\" data-id=\"5173bb0c\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<h6><span style=\"color: #0d344a;\"><b>Tumor Heterogeneity<\/b><\/span><\/h6><ul><li><span style=\"color: #0d344a;\">Tumor heterogeneity refers to differences observed among individual cells within a tumor, which directly impact prognosis and treatment response. In addition to intratumor heterogeneity, which pertains to differences among cells within a single tumor, there is also intertumor heterogeneity, which refers to differences observed at the population level. Tailoring the most effective treatment to different subpopulations can help personalize treatment plans for GBM patients.<\/span><\/li><\/ul>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-2b62b12f elementor-section-height-min-height elementor-section-boxed elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"2b62b12f\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-narrow\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-20329f07\" data-id=\"20329f07\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-30a04e0e elementor-widget elementor-widget-image\" data-id=\"30a04e0e\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"150\" height=\"150\" src=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2024\/04\/\u816b\u7624\u5fae\u74b0\u5883-150x150.png\" class=\"attachment-thumbnail size-thumbnail wp-image-7659\" alt=\"\" srcset=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2024\/04\/\u816b\u7624\u5fae\u74b0\u5883-150x150.png 150w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2024\/04\/\u816b\u7624\u5fae\u74b0\u5883-300x300.png 300w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2024\/04\/\u816b\u7624\u5fae\u74b0\u5883.png 400w\" sizes=\"(max-width: 150px) 100vw, 150px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-50329161\" data-id=\"50329161\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-4f18a88c elementor-widget elementor-widget-text-editor\" data-id=\"4f18a88c\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<h6><span style=\"color: #0d344a;\"><b>Tumor Microenvironment<\/b><\/span><\/h6><ul><li><p><span style=\"color: #0d344a;\"><strong>Cancer Stem Cells &#8211; Rapid Proliferation and Recurrence:<\/strong> Residual brain tumor cells contain a small number of cancer stem cells, which continuously divide and generate other tumor cells that do not possess stem cell properties, leading to tumor recurrence.<\/span><\/p><\/li><li><p><span style=\"color: #0d344a; font-size: 1.4rem;\"><b>Chemotherapy Drug Resistance:<\/b> Prolonged use of the current first-line chemotherapy drug, Temozolomide, leads to the production of O6-methylguanine methyltransferase (MGMT) in glioblastoma cells. MGMT repairs DNA damage caused by Temozolomide, rendering the tumor resistant to chemotherapy drugs and thus unable to effectively kill cancer cells.<\/span><\/p><\/li><li><p><span style=\"font-size: 1.4rem; color: #0d344a;\"><b>Immune Suppression:<\/b> Brain tumor cells achieve immune suppression by modulating the tumor microenvironment. This includes producing various immune-suppressive proteins or inhibiting antigen-presenting cells and attracting more immune-suppressive cells into the brain tumor microenvironment. This immune escape phenomenon accelerates disease progression.<\/span><\/p><\/li><\/ul>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-492528cd elementor-section-height-min-height elementor-section-boxed elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"492528cd\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-narrow\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-7d6151df\" data-id=\"7d6151df\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-7e1191be elementor-widget elementor-widget-image\" data-id=\"7e1191be\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"150\" height=\"150\" src=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2024\/04\/\u8166\u764c\u751f\u6d3b\u54c1\u8cea\u5dee-150x150.png\" class=\"attachment-thumbnail size-thumbnail wp-image-7671\" alt=\"\" srcset=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2024\/04\/\u8166\u764c\u751f\u6d3b\u54c1\u8cea\u5dee-150x150.png 150w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2024\/04\/\u8166\u764c\u751f\u6d3b\u54c1\u8cea\u5dee-300x300.png 300w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2024\/04\/\u8166\u764c\u751f\u6d3b\u54c1\u8cea\u5dee.png 400w\" sizes=\"(max-width: 150px) 100vw, 150px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-1c576ff\" data-id=\"1c576ff\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-56bc6671 elementor-widget elementor-widget-text-editor\" data-id=\"56bc6671\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<h6><span style=\"color: #0d344a;\"><b>Poor Quality of Life<\/b><\/span><\/h6><ul><li><p><span style=\"color: #0d344a;\">Patients undergoing brain cancer treatment often experience post-operative wound complications, pain, seizures, and edema. Additionally, the administration of chemotherapy drugs often leads to neurological side effects, <a href=\"https:\/\/www.efbiotech.com\/wordpress\/?page_id=6981\">further deteriorating the patients&#8217; quality of life and increasing the burden on their caregivers<\/a>.<\/span><\/p><\/li><\/ul>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<div class=\"elementor-element elementor-element-1aee1069 elementor-widget elementor-widget-spacer\" data-id=\"1aee1069\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-53bf0778 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"53bf0778\" data-element_type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f627a14 elementor-widget elementor-widget-text-editor\" data-id=\"f627a14\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<h6><span style=\"color: #ff914d;\"><b>Why Target Glioblastoma Multiforme (GBM)<\/b><\/span><\/h6><ul><li><p><span style=\"color: #ff914d;\"><strong>There have been no new advancements in Glioblastoma Multiforme (GBM) treatment for nearly 20 years<\/strong><\/span><span style=\"color: #0d344a;\">, compared to other cancer treatments such as lung cancer, where over 30 drugs have been introduced in the past two decades.<\/span><\/p><\/li><li><p><span style=\"color: #0d344a;\">This highlights the difficulties and challenges faced globally in the treatment of brain cancer, which is a primary reason for our active involvement in this field.<\/span><\/p><\/li><\/ul>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-d32161b elementor-widget elementor-widget-image\" data-id=\"d32161b\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"800\" height=\"450\" src=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2024\/03\/No-New-Advancements-in-GBM-Treatment-for-20-Years-1024x576.png\" class=\"attachment-large size-large wp-image-7060\" alt=\"No New Advancements in GBM Treatment for 20 Years\" srcset=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2024\/03\/No-New-Advancements-in-GBM-Treatment-for-20-Years-1024x576.png 1024w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2024\/03\/No-New-Advancements-in-GBM-Treatment-for-20-Years-300x169.png 300w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2024\/03\/No-New-Advancements-in-GBM-Treatment-for-20-Years-768x432.png 768w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2024\/03\/No-New-Advancements-in-GBM-Treatment-for-20-Years.png 1366w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-31edf994 elementor-widget elementor-widget-image\" data-id=\"31edf994\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"800\" height=\"450\" src=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2024\/04\/Cerebraca-wafer-overcome-the-key-challenge-1-1024x576.png\" class=\"attachment-large size-large wp-image-7703\" alt=\"\" srcset=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2024\/04\/Cerebraca-wafer-overcome-the-key-challenge-1-1024x576.png 1024w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2024\/04\/Cerebraca-wafer-overcome-the-key-challenge-1-300x169.png 300w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2024\/04\/Cerebraca-wafer-overcome-the-key-challenge-1-768x432.png 768w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2024\/04\/Cerebraca-wafer-overcome-the-key-challenge-1.png 1366w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-347738e elementor-section-height-min-height elementor-section-boxed elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"347738e\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-narrow\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-239c6dd3\" data-id=\"239c6dd3\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-2b914ac4 elementor-widget elementor-widget-text-editor\" data-id=\"2b914ac4\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<h6><span style=\"color: #0d344a;\"><strong><a href=\"https:\/\/www.efbiotech.com\/wordpress\/?page_id=1778\">Cerebraca\u00ae Wafer<\/a> is designed to overcome key challenges in the treatment of Glioblastoma Multiforme (GBM), providing a solid foundation for superior clinical outcomes<\/strong><\/span><\/h6><p><span style=\"color: #0d344a;\">One key aspect of Cerebraca\u00ae Wafer is its ability to eradicate residual tumor cells and suppress cancer stem cells after brain surgery. Implanted at the surgical resection site, Cerebraca\u00ae Wafer creates a local environment with high drug concentration, excellent penetration, and sustained release for 30 days to inhibit the growth of remaining tumor cells.<\/span><\/p><p><span style=\"color: #0d344a;\">Following tumor resection, the regenerative microenvironment further enhances the malignancy of residual GBM cells. Tumor heterogeneity limits the effectiveness of single-targeted therapy. Cancer stem cells, rapid proliferation, and recurrence contribute to disease progression. Additionally, chemotherapy drug resistance and immune suppression lead to the failure of conventional treatments, including chemotherapy and immunotherapy. To address these multifaceted challenges, the <a href=\"https:\/\/www.efbiotech.com\/wordpress\/?page_id=7318\">active ingredient EF-API-001<\/a> in Cerebraca\u00ae Wafer is a multifunctional drug that targets cancer stem cells, reduces chemotherapy drug resistance, and activates the immune system. Unlike currently available treatments, which often result in neurological side effects and increased caregiver burden, clinical trial results with Cerebraca\u00ae Wafer show that the treatment does not cause additional adverse events, thus improving quality of life post-treatment.<\/span><\/p><p><b><span style=\"color: #0d344a;\">More about Cerebraca\u00ae Wafer\ud83d\udc49<\/span> <a href=\"https:\/\/www.efbiotech.com\/wordpress\/?page_id=1778\">read more<\/a><\/b><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<div class=\"elementor-element elementor-element-da6c3d7 elementor-widget elementor-widget-text-editor\" data-id=\"da6c3d7\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-8cf4733 elementor-widget elementor-widget-heading\" data-id=\"8cf4733\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<span class=\"elementor-heading-title elementor-size-default\">This article is provided for informational purposes only regarding industry information. The development of new drugs involves lengthy timelines, high financial investments, and is not guaranteed to be successful. These factors may expose investors to risks, and therefore, investors should exercise caution and prudence when making investment decisions.<\/span>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-f70b6b0 elementor-section-stretched elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"f70b6b0\" data-element_type=\"section\" data-settings=\"{&quot;stretch_section&quot;:&quot;section-stretched&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-5675239\" data-id=\"5675239\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-2264ed0 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"2264ed0\" data-element_type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-8d125df elementor-widget elementor-widget-heading\" data-id=\"8d125df\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Development Pipeline<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-db8ab87 elementor-section-full_width elementor-section-stretched elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"db8ab87\" data-element_type=\"section\" data-settings=\"{&quot;stretch_section&quot;:&quot;section-stretched&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-narrow\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-fb32729\" data-id=\"fb32729\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-95e3736 elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"95e3736\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-7d62a42\" data-id=\"7d62a42\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-d484487 elementor-widget elementor-widget-image\" data-id=\"d484487\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"400\" height=\"400\" src=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/pipeline-1.png\" class=\"attachment-large size-large wp-image-1709\" alt=\"Pepline - EF-001\" srcset=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/pipeline-1.png 400w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/pipeline-1-300x300.png 300w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/pipeline-1-150x150.png 150w\" sizes=\"(max-width: 400px) 100vw, 400px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-bbacae2 elementor-align-center e-transform e-transform elementor-widget elementor-widget-button\" data-id=\"bbacae2\" data-element_type=\"widget\" data-settings=\"{&quot;_transform_scale_effect&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:1.03,&quot;sizes&quot;:[]},&quot;_transform_scaleX_effect_hover&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:1.1,&quot;sizes&quot;:[]},&quot;_transform_scaleY_effect_hover&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:1.1,&quot;sizes&quot;:[]},&quot;_transform_scale_effect_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_scale_effect_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_scaleX_effect_hover_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_scaleX_effect_hover_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_scaleY_effect_hover_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_scaleY_effect_hover_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t<a href=\"https:\/\/www.efbiotech.com\/wordpress\/?page_id=1778\" class=\"elementor-button-link elementor-button elementor-size-sm\" role=\"button\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-text\">EF-001<\/span>\n\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-5600407\" data-id=\"5600407\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-95c3f2f elementor-widget elementor-widget-image\" data-id=\"95c3f2f\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"400\" height=\"400\" src=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/pepline-2.png\" class=\"attachment-large size-large wp-image-1710\" alt=\"Pepline - EF-009\" srcset=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/pepline-2.png 400w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/pepline-2-300x300.png 300w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/pepline-2-150x150.png 150w\" sizes=\"(max-width: 400px) 100vw, 400px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-75dd076 elementor-align-center e-transform e-transform elementor-widget elementor-widget-button\" data-id=\"75dd076\" data-element_type=\"widget\" data-settings=\"{&quot;_transform_scale_effect&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:1.03,&quot;sizes&quot;:[]},&quot;_transform_scaleX_effect_hover&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:1.1,&quot;sizes&quot;:[]},&quot;_transform_scaleY_effect_hover&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:1.1,&quot;sizes&quot;:[]},&quot;_transform_scale_effect_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_scale_effect_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_scaleX_effect_hover_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_scaleX_effect_hover_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_scaleY_effect_hover_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_scaleY_effect_hover_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t<a href=\"https:\/\/www.efbiotech.com\/wordpress\/?page_id=1870\" class=\"elementor-button-link elementor-button elementor-size-sm\" role=\"button\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-text\">EF-009<\/span>\n\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-ac97389\" data-id=\"ac97389\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-17e9439 elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"17e9439\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-f2ae4c9\" data-id=\"f2ae4c9\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-bf4d6ab elementor-widget elementor-widget-image\" data-id=\"bf4d6ab\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"400\" height=\"400\" src=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/pepline-3.png\" class=\"attachment-large size-large wp-image-1711\" alt=\"Pepline - HK-001\" srcset=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/pepline-3.png 400w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/pepline-3-300x300.png 300w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/pepline-3-150x150.png 150w\" sizes=\"(max-width: 400px) 100vw, 400px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-22d7aed elementor-align-center e-transform e-transform elementor-widget elementor-widget-button\" data-id=\"22d7aed\" data-element_type=\"widget\" data-settings=\"{&quot;_transform_scale_effect&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:1.03,&quot;sizes&quot;:[]},&quot;_transform_scaleX_effect_hover&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:1.1,&quot;sizes&quot;:[]},&quot;_transform_scaleY_effect_hover&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:1.1,&quot;sizes&quot;:[]},&quot;_transform_scale_effect_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_scale_effect_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_scaleX_effect_hover_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_scaleX_effect_hover_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_scaleY_effect_hover_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_scaleY_effect_hover_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t<a href=\"https:\/\/www.efbiotech.com\/wordpress\/?page_id=3417\" class=\"elementor-button-link elementor-button elementor-size-sm\" role=\"button\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-text\">HK-001<\/span>\n\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-5737ad9\" data-id=\"5737ad9\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-292deeb elementor-widget elementor-widget-image\" data-id=\"292deeb\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"400\" height=\"400\" src=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/Pepline-4-1.png\" class=\"attachment-large size-large wp-image-1713\" alt=\"Pepline - EF-031\" srcset=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/Pepline-4-1.png 400w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/Pepline-4-1-300x300.png 300w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/Pepline-4-1-150x150.png 150w\" sizes=\"(max-width: 400px) 100vw, 400px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-e01f7b3 elementor-align-center e-transform e-transform elementor-widget elementor-widget-button\" data-id=\"e01f7b3\" data-element_type=\"widget\" data-settings=\"{&quot;_transform_scale_effect&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:1.03,&quot;sizes&quot;:[]},&quot;_transform_scaleX_effect_hover&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:1.1,&quot;sizes&quot;:[]},&quot;_transform_scaleY_effect_hover&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:1.1,&quot;sizes&quot;:[]},&quot;_transform_scale_effect_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_scale_effect_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_scaleX_effect_hover_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_scaleX_effect_hover_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_scaleY_effect_hover_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_scaleY_effect_hover_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t<a href=\"https:\/\/www.efbiotech.com\/wordpress\/?page_id=5401\" class=\"elementor-button-link elementor-button elementor-size-sm\" role=\"button\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-text\">EF-031<\/span>\n\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Facing Challenges in<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_sitemap_exclude":false,"_sitemap_priority":"","_sitemap_frequency":"","footnotes":""},"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.efbiotech.com\/wordpress\/index.php?rest_route=\/wp\/v2\/pages\/7688"}],"collection":[{"href":"https:\/\/www.efbiotech.com\/wordpress\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.efbiotech.com\/wordpress\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.efbiotech.com\/wordpress\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.efbiotech.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=7688"}],"version-history":[{"count":10,"href":"https:\/\/www.efbiotech.com\/wordpress\/index.php?rest_route=\/wp\/v2\/pages\/7688\/revisions"}],"predecessor-version":[{"id":8959,"href":"https:\/\/www.efbiotech.com\/wordpress\/index.php?rest_route=\/wp\/v2\/pages\/7688\/revisions\/8959"}],"wp:attachment":[{"href":"https:\/\/www.efbiotech.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=7688"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}