{"id":5808,"date":"2023-07-17T14:14:05","date_gmt":"2023-07-17T06:14:05","guid":{"rendered":"http:\/\/www.efbiotech.com\/wordpress\/?page_id=5808"},"modified":"2024-08-29T11:36:26","modified_gmt":"2024-08-29T03:36:26","slug":"orphan-drug","status":"publish","type":"page","link":"https:\/\/www.efbiotech.com\/wordpress\/?page_id=5808","title":{"rendered":"Orphan Drug"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"5808\" class=\"elementor elementor-5808\">\n\t\t\t\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-5f0d77da elementor-section-full_width elementor-section-stretched elementor-hidden-mobile elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"5f0d77da\" data-element_type=\"section\" data-settings=\"{&quot;stretch_section&quot;:&quot;section-stretched&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-3f1fc001\" data-id=\"3f1fc001\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-293d6ab8 elementor-widget elementor-widget-image\" data-id=\"293d6ab8\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.11.5 - 14-03-2023 *\/\n.elementor-widget-image{text-align:center}.elementor-widget-image a{display:inline-block}.elementor-widget-image a img[src$=\".svg\"]{width:48px}.elementor-widget-image img{vertical-align:middle;display:inline-block}<\/style>\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"1366\" height=\"456\" src=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/06\/14.png\" class=\"attachment-full size-full wp-image-4120\" alt=\"\" srcset=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/06\/14.png 1366w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/06\/14-300x100.png 300w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/06\/14-1024x342.png 1024w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/06\/14-768x256.png 768w\" sizes=\"(max-width: 1366px) 100vw, 1366px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-67fbbdf5 elementor-widget elementor-widget-spacer\" data-id=\"67fbbdf5\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.11.5 - 14-03-2023 *\/\n.elementor-column .elementor-spacer-inner{height:var(--spacer-size)}.e-con{--container-widget-width:100%}.e-con-inner>.elementor-widget-spacer,.e-con>.elementor-widget-spacer{width:var(--container-widget-width,var(--spacer-size));--align-self:var(--container-widget-align-self,initial);--flex-shrink:0}.e-con-inner>.elementor-widget-spacer>.elementor-widget-container,.e-con-inner>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer,.e-con>.elementor-widget-spacer>.elementor-widget-container,.e-con>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer{height:100%}.e-con-inner>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer>.elementor-spacer-inner,.e-con>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer>.elementor-spacer-inner{height:var(--container-widget-height,var(--spacer-size))}<\/style>\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-3eaf67d9 elementor-section-full_width elementor-section-stretched elementor-hidden-desktop elementor-hidden-tablet elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"3eaf67d9\" data-element_type=\"section\" data-settings=\"{&quot;stretch_section&quot;:&quot;section-stretched&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-64eab393\" data-id=\"64eab393\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-592ef727 elementor-widget-mobile__width-inherit elementor-widget elementor-widget-image\" data-id=\"592ef727\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"1080\" height=\"1080\" src=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/06\/23.png\" class=\"attachment-full size-full wp-image-4914\" alt=\"\" srcset=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/06\/23.png 1080w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/06\/23-300x300.png 300w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/06\/23-1024x1024.png 1024w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/06\/23-150x150.png 150w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/06\/23-768x768.png 768w\" sizes=\"(max-width: 1080px) 100vw, 1080px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1ee41018 elementor-widget elementor-widget-spacer\" data-id=\"1ee41018\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-15c56d8c elementor-section-stretched elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"15c56d8c\" data-element_type=\"section\" data-settings=\"{&quot;stretch_section&quot;:&quot;section-stretched&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-1ea07eda\" data-id=\"1ea07eda\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-6905b8ea elementor-widget elementor-widget-heading\" data-id=\"6905b8ea\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.11.5 - 14-03-2023 *\/\n.elementor-heading-title{padding:0;margin:0;line-height:1}.elementor-widget-heading .elementor-heading-title[class*=elementor-size-]>a{color:inherit;font-size:inherit;line-height:inherit}.elementor-widget-heading .elementor-heading-title.elementor-size-small{font-size:15px}.elementor-widget-heading .elementor-heading-title.elementor-size-medium{font-size:19px}.elementor-widget-heading .elementor-heading-title.elementor-size-large{font-size:29px}.elementor-widget-heading .elementor-heading-title.elementor-size-xl{font-size:39px}.elementor-widget-heading .elementor-heading-title.elementor-size-xxl{font-size:59px}<\/style><h1 class=\"elementor-heading-title elementor-size-medium\">Orphan Drug<\/h1>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-28e1f3e elementor-widget elementor-widget-text-editor\" data-id=\"28e1f3e\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.11.5 - 14-03-2023 *\/\n.elementor-widget-text-editor.elementor-drop-cap-view-stacked .elementor-drop-cap{background-color:#818a91;color:#fff}.elementor-widget-text-editor.elementor-drop-cap-view-framed .elementor-drop-cap{color:#818a91;border:3px solid;background-color:transparent}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap{margin-top:8px}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap-letter{width:1em;height:1em}.elementor-widget-text-editor .elementor-drop-cap{float:left;text-align:center;line-height:1;font-size:50px}.elementor-widget-text-editor .elementor-drop-cap-letter{display:inline-block}<\/style>\t\t\t\t<p style=\"text-align: center;\"><span style=\"color: #ffff00;\"><strong>When a rare disease lacks effective treatment options, patients and their families often face significant challenges and difficulties.<\/strong><\/span><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-54d1f597 elementor-widget elementor-widget-text-editor\" data-id=\"54d1f597\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><span style=\"color: #0d344a;\">Orphan drugs refer to medications used to treat rare diseases, which are often characterized by a limited number of affected individuals and a lack of adequate medical resources, leading to neglect or insufficient treatment options.<\/span><\/p><p><span style=\"color: #0d344a;\">However, for patients and families suffering from rare diseases, these orphan drugs represent their last hope. These medications may be their only lifeline, providing them with a chance to regain their health and improve their quality of life.<\/span><\/p><p><span style=\"color: #0d344a;\">For the general public, it may be difficult to comprehend the pain and helplessness experienced by those suffering from rare diseases. However, we can imagine what it would be like if these rare diseases were to affect ourselves or our loved ones. Faced with the reality of inadequate treatment options, what would we do?<\/span><\/p><p><span style=\"color: #0d344a;\">Orphan drugs are not just medications; they represent a call to humanity and a reverence for life. The development and introduction of these drugs not only offer hope to patients but also exemplify human empathy and compassion.<\/span><\/p><p><strong><span style=\"color: #0d344a;\">Therefore, we should support and promote the research and dissemination of orphan drugs, providing more assistance and support to those with rare diseases. By doing so, we can enable them to regain their health and quality of life, rekindling their hope and confidence in the future.<\/span><\/strong><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2efdde11 elementor-widget elementor-widget-spacer\" data-id=\"2efdde11\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1ad386a5 elementor-widget elementor-widget-heading\" data-id=\"1ad386a5\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-medium\">Advantages and Niches of Orphan Drug Development<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-1eea4f6f elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"1eea4f6f\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-inner-column elementor-element elementor-element-54545b58\" data-id=\"54545b58\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-5f084274 elementor-widget elementor-widget-image\" data-id=\"5f084274\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"400\" height=\"400\" src=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/04\/hope.png\" class=\"attachment-full size-full wp-image-2798\" alt=\"\" srcset=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/04\/hope.png 400w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/04\/hope-300x300.png 300w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/04\/hope-150x150.png 150w\" sizes=\"(max-width: 400px) 100vw, 400px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-66 elementor-inner-column elementor-element elementor-element-309a1332\" data-id=\"309a1332\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-6fb1165c elementor-widget elementor-widget-text-editor\" data-id=\"6fb1165c\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<ul><li><span style=\"color: #0d344a;\"><strong>Blue Ocean Market:<\/strong> In the United States, rare diseases are defined as conditions affecting fewer than 200,000 patients (e.g., Taiwan&#8217;s Ministry of Health and Welfare defines it as below one-thousandth of the population; Japan defines it as below 50,000 individuals). There are over 7,000 rare diseases, but the number of pharmaceutical companies developing drugs for these conditions is limited, resulting in a scarcity of therapies targeting specific rare diseases.<\/span><\/li><\/ul><ul><li><span style=\"color: #0d344a;\"><strong>Government Incentives:<\/strong> Governments provide benefits such as tax credits for orphan drugs, seven years of market exclusivity, and advantages in drug pricing schemes, among others.<\/span><\/li><\/ul><ul><li><span style=\"color: #0d344a;\"><strong>Favorable Clinical Trial Design:<\/strong> Orphan drug trials often adopt single-arm (non-placebo) designs with an open-label approach. Additionally, they may not require a phase I safety trial or can combine phase II and III trials when patient populations are extremely small.<\/span><\/li><\/ul><ul><li><span style=\"color: #0d344a;\"><b>Expedited Qualification Review: <\/b>The U.S. Food and Drug Administration (FDA) offers accelerated programs for applicants, such as Fast Track, Breakthrough Therapy, Priority Review, Accelerated Approval, and unique funding opportunities.<\/span><\/li><\/ul>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<div class=\"elementor-element elementor-element-5972cef7 elementor-widget elementor-widget-spacer\" data-id=\"5972cef7\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-17f55d2d elementor-widget elementor-widget-heading\" data-id=\"17f55d2d\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-medium\">Orphan Drug Designation<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-16e6fbb6 elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"16e6fbb6\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-inner-column elementor-element elementor-element-6f53379\" data-id=\"6f53379\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-52b37fb6 elementor-widget elementor-widget-image\" data-id=\"52b37fb6\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"400\" height=\"400\" src=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/04\/Report.png\" class=\"attachment-full size-full wp-image-2799\" alt=\"\" srcset=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/04\/Report.png 400w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/04\/Report-300x300.png 300w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/04\/Report-150x150.png 150w\" sizes=\"(max-width: 400px) 100vw, 400px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-66 elementor-inner-column elementor-element elementor-element-4d2bf72f\" data-id=\"4d2bf72f\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-73ed3df elementor-widget elementor-widget-text-editor\" data-id=\"73ed3df\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<ul><li><span style=\"color: #0d344a;\">The Orphan Drug Act in the United States allows sponsors to apply for a special status known as &#8220;orphan designation&#8221; or &#8220;orphan status&#8221; to drugs intended to treat rare diseases.<\/span><\/li><\/ul><ul><li><span style=\"color: #0d344a;\">Before sponsors can seek drug approval and incentives like orphan drug grants under the Orphan Drug Act, they must first apply for and obtain orphan drug designation from the FDA. Applications can be submitted at any stage of drug development, but the FDA recommends applying before submitting a new drug clinical trial application to clarify clinical trial planning and design.<\/span><\/li><\/ul><ul><li><span style=\"color: #0d344a;\">During the submission for qualification review, applicants must provide the required documentation outlined in CFR 316.20 and 316.21. Clinical data, animal studies, or in vitro data can be provided by the applicant, but sufficient published literature may also be acceptable.<\/span><\/li><\/ul><ul><li><span style=\"color: #0d344a;\">Multiple sponsors for the same drug intended to treat the same rare disease may obtain orphan drug designation, but only the sponsor receiving the first FDA approval can obtain orphan drug marketing exclusivity.<\/span><\/li><\/ul>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<div class=\"elementor-element elementor-element-2114e9b2 elementor-widget elementor-widget-spacer\" data-id=\"2114e9b2\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-36812c25 elementor-widget elementor-widget-heading\" data-id=\"36812c25\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-medium\">Orphan Drug Benefits in Some Other Major Countries\n(https:\/\/doi.org\/10.1371\/journal.pone.0140002)<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-6b505bf2 elementor-widget elementor-widget-text-editor\" data-id=\"6b505bf2\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<table width=\"1562\"><tbody><tr><td width=\"276\"><p><span style=\"color: #0d344a;\"><b>Country<\/b><\/span><\/p><\/td><td width=\"171\"><p><span style=\"color: #0d344a;\"><b>Orphan Drug Designation<\/b><\/span><\/p><\/td><td width=\"171\"><p><span style=\"color: #0d344a;\"><b>Market Exclusivity<\/b><\/span><\/p><\/td><td width=\"319\"><p><span style=\"font-family: 'Open Sans', sans-serif; font-size: 1.6rem; color: #0d344a;\"><b>Financial Incentives<\/b><\/span><\/p><\/td><td width=\"310\"><p data-pm-slice=\"1 1 [&quot;table&quot;,{&quot;id&quot;:&quot;ntb020do6y0&quot;,&quot;hideLabel&quot;:false,&quot;align&quot;:null,&quot;size&quot;:null,&quot;smallerFont&quot;:false,&quot;suggestionId&quot;:null,&quot;suggestionTimestamp&quot;:null,&quot;suggestionUserId&quot;:null,&quot;suggestionDiscussionId&quot;:null,&quot;suggestionKind&quot;:null,&quot;suggestionOriginalAttrs&quot;:null},&quot;table_row&quot;,{&quot;suggestionId&quot;:null,&quot;suggestionTimestamp&quot;:null,&quot;suggestionUserId&quot;:null,&quot;suggestionDiscussionId&quot;:null,&quot;suggestionKind&quot;:null,&quot;suggestionOriginalAttrs&quot;:null},&quot;table_cell&quot;,{&quot;colspan&quot;:1,&quot;rowspan&quot;:1,&quot;colwidth&quot;:null,&quot;background&quot;:null,&quot;suggestionId&quot;:null,&quot;suggestionTimestamp&quot;:null,&quot;suggestionUserId&quot;:null,&quot;suggestionDiscussionId&quot;:null,&quot;suggestionKind&quot;:null,&quot;suggestionOriginalAttrs&quot;:null}]\"><span style=\"color: #0d344a;\"><b>Nonfinancial Incentives<\/b><\/span><\/p><\/td><td width=\"315\"><p><span style=\"color: #0d344a;\"><b>Pricing<\/b><\/span><\/p><\/td><\/tr><tr><td width=\"276\"><p><span style=\"color: #0d344a;\"><b>Australia<\/b><\/span><\/p><\/td><td width=\"171\"><p><span style=\"color: #0d344a;\">Yes<\/span><\/p><\/td><td width=\"171\"><p><span style=\"color: #0d344a;\">No<\/span><\/p><\/td><td width=\"319\"><p><span style=\"color: #0d344a;\">Fee reduction for marketing authorization approval<\/span><\/p><\/td><td width=\"310\"><p><span style=\"color: #0d344a;\">Pre-licensing access, regulatory assistance<\/span><\/p><\/td><td width=\"315\"><p><span style=\"color: #0d344a;\">Fixed\u00a0<\/span><\/p><\/td><\/tr><tr><td width=\"276\"><p><span style=\"color: #0d344a;\"><b>Canada<\/b><\/span><\/p><\/td><td width=\"171\"><p><span style=\"color: #0d344a;\">No<\/span><\/p><\/td><td width=\"171\"><p><span style=\"color: #0d344a;\">No<\/span><\/p><\/td><td width=\"319\"><p><span style=\"color: #0d344a;\">Tax incentives, fee reduction for marketing authorization<\/span><\/p><\/td><td width=\"310\"><p><span style=\"color: #0d344a;\">Pre-licensing access, scientific advice, protocol assistance, regulatory assistance<\/span><\/p><\/td><td width=\"315\"><p><span style=\"color: #0d344a;\">Reference pricing<\/span><\/p><\/td><\/tr><tr><td width=\"276\"><p><span style=\"color: #0d344a;\"><b>Japan<\/b><\/span><\/p><\/td><td width=\"171\"><p><span style=\"color: #0d344a;\">Yes<\/span><\/p><\/td><td width=\"171\"><p><span style=\"color: #0d344a;\">10 years<\/span><\/p><\/td><td width=\"319\"><p><span style=\"color: #0d344a;\">Financial subsidies, tax credits, user fee waivers<\/span><\/p><\/td><td width=\"310\"><p><span style=\"color: #0d344a;\">Priority review, fast track approval, free protocol assistance<\/span><\/p><\/td><td width=\"315\"><p><span style=\"color: #0d344a;\">Fixed = cost + 10%<\/span><\/p><\/td><\/tr><tr><td width=\"276\"><p><span style=\"color: #0d344a;\"><b>EU5<\/b><\/span><span style=\"color: #0d344a;\"><b>(France<\/b><b>, Germany<\/b><b>, Italy<\/b><b>, Spain<\/b><b>, U.K.<\/b><b>)<\/b><\/span><\/p><\/td><td width=\"171\"><p><span style=\"color: #0d344a;\">No<\/span><\/p><\/td><td width=\"171\"><p><span style=\"color: #0d344a;\">10 years<\/span><\/p><\/td><td width=\"319\"><p><span style=\"color: #0d344a;\">Reduced rebates in Spain and tax exemptions in France<\/span><\/p><\/td><td width=\"310\"><p><span style=\"color: #0d344a;\">Pre-licensing access in all EU5 countries, protocol assistance and scientific advice in France and Italy<\/span><\/p><\/td><td width=\"315\"><p><span style=\"color: #0d344a;\">Free pricing in Germany, reference pricing in Italy, fixed pricing in Spain and the U.K, and price negotiations in France<\/span><\/p><\/td><\/tr><\/tbody><\/table>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c994138 elementor-widget elementor-widget-text-editor\" data-id=\"c994138\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<h6><span style=\"color: #0d344a;\"><strong>Supplementary Information<\/strong><\/span><\/h6><h6><span style=\"color: #0d344a;\"><strong>The Rare Disease and Orphan Drug Act (Taiwan)<\/strong><\/span><\/h6><ul><li><span style=\"color: #0d344a;\">Taiwan has established comprehensive legislation and incentives related to orphan drugs, offering a promising pathway for new drug developers.\u00a0<\/span><\/li><li><span style=\"color: #0d344a;\">Taiwan adopts a healthcare budget allocation approach that provides dedicated funding for specific items. Patients who are recognized under the rare disease review process are entitled to use orphan drugs covered by the National Health Insurance (NHI) and special nutritional supplements necessary for sustaining life, ensuring the protection of patient rights.<\/span><\/li><li><span style=\"color: #0d344a;\">The Rare Disease and Orphan Drug Act was established in 2000, with the most recent revision enacted in 2015. Under this law, orphan drugs in Taiwan are granted 10 years of market exclusivity (the license is valid for ten years, during which the central authority will not accept registration applications for similar drugs).<\/span><\/li><\/ul><p><span style=\"color: #0d344a;\"><strong>Rare Diseases in China<\/strong><\/span><\/p><ul><li><p><span style=\"color: #0d344a;\">China has issued two notifications of rare disease catalogs, which serve as the basis for revising guidelines and standards for the diagnosis and treatment of rare diseases. Indications and products included in the rare disease catalog are granted priority review and inclusion in the national medical insurance catalog; however, there is currently no market exclusivity or additional incentive measures in place.<\/span><\/p><\/li><li><p><span style=\"color: #0d344a;\">In 2018, China published the first notification of the rare disease catalog, which included 121 drugs.<\/span><\/p><\/li><li><p><span style=\"color: #0d344a;\">In 2023, the second notification of the rare disease catalog was released, adding 86 more drugs to the list.<\/span><\/p><\/li><\/ul>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-67ad45f5 elementor-widget elementor-widget-spacer\" data-id=\"67ad45f5\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2c3e141f elementor-widget elementor-widget-heading\" data-id=\"2c3e141f\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-medium\">Major Financial Incentives (United States)<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-2f02e835 elementor-section-height-min-height elementor-section-boxed elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"2f02e835\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-narrow\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-8557dd8\" data-id=\"8557dd8\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-40669822 elementor-widget elementor-widget-image\" data-id=\"40669822\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"150\" height=\"150\" src=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/04\/\u8c41\u514d-150x150.png\" class=\"attachment-thumbnail size-thumbnail wp-image-2800\" alt=\"\" srcset=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/04\/\u8c41\u514d-150x150.png 150w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/04\/\u8c41\u514d-300x300.png 300w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/04\/\u8c41\u514d.png 709w\" sizes=\"(max-width: 150px) 100vw, 150px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-6c8a45bb\" data-id=\"6c8a45bb\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-406e2c8c elementor-widget elementor-widget-text-editor\" data-id=\"406e2c8c\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<h6><strong><span style=\"color: #0d344a;\">Orphan Drug Tax Credits (ODTC)<\/span><\/strong><\/h6><p><span style=\"color: #0d344a;\"> Developers of orphan drugs are eligible for a tax credit that covers 50% of qualified clinical research and development costs, along with a seven-year market exclusivity. Since the introduction of this tax credit in 1983, the FDA has approved over 500 orphan drugs, a significant increase compared to only 10 approvals before the incentive was introduced.<\/span><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-1ed4d6b7 elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"1ed4d6b7\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-narrow\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-637fbf69\" data-id=\"637fbf69\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-1c4f552b elementor-widget elementor-widget-image\" data-id=\"1c4f552b\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"150\" height=\"150\" src=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/04\/free-150x150.png\" class=\"attachment-thumbnail size-thumbnail wp-image-2801\" alt=\"\" srcset=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/04\/free-150x150.png 150w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/04\/free-300x300.png 300w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/04\/free.png 709w\" sizes=\"(max-width: 150px) 100vw, 150px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-7a158bd8\" data-id=\"7a158bd8\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-17c9d6a2 elementor-widget elementor-widget-text-editor\" data-id=\"17c9d6a2\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<h6><span style=\"color: #0d344a;\"><b><strong>Prescription Drug User Fee Act (PDUFA) Waiver<\/strong><\/b><\/span><\/h6><p><span style=\"color: #0d344a;\">The FDA has the authority to assess and collect user fees for certain drug and biological product applications. Pharmaceutical companies are required to pay fees for certain new drug applications, biological product applications, and supplemental applications submitted for review by the agency, which can amount to approximately $2.2 million. However, human drug applications\/biological product applications for orphan drugs are exempt from application fees, unless the application includes indications beyond rare diseases.<\/span><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-3116bad8 elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"3116bad8\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-narrow\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-5b921467\" data-id=\"5b921467\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-5a35b17d elementor-widget elementor-widget-image\" data-id=\"5a35b17d\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"150\" height=\"150\" src=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/04\/exclusive-150x150.png\" class=\"attachment-thumbnail size-thumbnail wp-image-2802\" alt=\"\" srcset=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/04\/exclusive-150x150.png 150w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/04\/exclusive-300x300.png 300w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/04\/exclusive.png 709w\" sizes=\"(max-width: 150px) 100vw, 150px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-130e5aab\" data-id=\"130e5aab\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-348c09d4 elementor-widget elementor-widget-text-editor\" data-id=\"348c09d4\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<h6><span style=\"color: #0d344a;\"><strong>Market Exclusivity and Pricing<\/strong><\/span><\/h6><p><span style=\"color: #0d344a;\">To allow orphan drug developers a few years to recoup their development costs, market exclusivity is granted. The FDA&#8217;s orphan drug market exclusivity period starts from the date of new drug application approval and lasts for seven years. The pricing of orphan drugs is unique and designed to enable manufacturers to recover development costs from a small number of patients. Unlike the pricing models of other drugs, orphan drug pricing is often based on the patients&#8217; ability to pay. Due to market exclusivity and a lack of alternative treatments, orphan drugs are relatively expensive. Considering the limited treatment options and the life-threatening or chronic nature of many rare diseases, higher pricing is generally more acceptable.<\/span><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<div class=\"elementor-element elementor-element-68efc563 elementor-widget elementor-widget-spacer\" data-id=\"68efc563\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-41002651 elementor-widget elementor-widget-spacer\" data-id=\"41002651\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1d9211fc elementor-widget elementor-widget-heading\" data-id=\"1d9211fc\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-medium\">Eligibility for Expedited Approval Processes (United States)<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1ba9def2 elementor-widget elementor-widget-spacer\" data-id=\"1ba9def2\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2da565e2 elementor-widget elementor-widget-heading\" data-id=\"2da565e2\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Successful Speedy Approval Process<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-41b1718d elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"41b1718d\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-6bf3416c\" data-id=\"6bf3416c\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-4086b92b elementor-widget elementor-widget-heading\" data-id=\"4086b92b\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Designation (Reply within 60-days)<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-258e5cf2 elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"258e5cf2\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-1a9044eb\" data-id=\"1a9044eb\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-54e9befd elementor-widget__width-initial elementor-widget elementor-widget-heading\" data-id=\"54e9befd\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Fast Track<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3ebebd8d elementor-widget__width-initial elementor-widget elementor-widget-heading\" data-id=\"3ebebd8d\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Break Through<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-472aa815 elementor-widget__width-initial elementor-widget elementor-widget-heading\" data-id=\"472aa815\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Priority Review<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-6102d7d1 elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"6102d7d1\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-5f176f24\" data-id=\"5f176f24\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-299658c9 elementor-widget__width-initial elementor-widget elementor-widget-heading\" data-id=\"299658c9\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<span class=\"elementor-heading-title elementor-size-default\">Used for treating severe diseases and addressing the unmet medical needs, drug development for these purposes accelerates the FDA review process. The qualification of a drug for treating severe diseases depends on factors such as its positive impact on survival, daily functioning, or whether the disease would progress from mild to more severe symptoms if left untreated.<\/span>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-6469f981 elementor-widget__width-initial elementor-widget elementor-widget-heading\" data-id=\"6469f981\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<span class=\"elementor-heading-title elementor-size-default\">Intended for the treatment of severe diseases and superior to existing therapeutic methods, these drugs show preliminary clinical evidence of potentially demonstrating a significant improvement in at least one important clinical endpoint. The magnitude of the treatment effect and observed clinically meaningful outcomes contribute to the significant breakthrough improvement.<\/span>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-260bacae elementor-widget__width-initial elementor-widget elementor-widget-heading\" data-id=\"260bacae\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<span class=\"elementor-heading-title elementor-size-default\">Trial sponsors must submit a drug application (original or efficacy supplement) targeting the treatment of severe diseases. If the drug can significantly enhance its safety or efficacy, it may be granted approval.<\/span>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<div class=\"elementor-element elementor-element-53e1afd2 elementor-widget elementor-widget-spacer\" data-id=\"53e1afd2\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-45726ee8 elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"45726ee8\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-9d5c4ab\" data-id=\"9d5c4ab\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-3559de41 elementor-widget elementor-widget-heading\" data-id=\"3559de41\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Approval Pathway<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-43f239b1 elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"43f239b1\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-6adb1267\" data-id=\"6adb1267\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-19e4cc9e elementor-widget elementor-widget-heading\" data-id=\"19e4cc9e\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Accelerated Approval<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-3c062d42 elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"3c062d42\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-33f56b2a\" data-id=\"33f56b2a\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-403e710a elementor-widget elementor-widget-heading\" data-id=\"403e710a\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<span class=\"elementor-heading-title elementor-size-default\">The Accelerated Approval regulation established by the FDA in 1992 allows drugs targeting severe diseases and addressing unmet therapeutic needs to be approved based on surrogate endpoints. These endpoints should be markers, such as laboratory measurements or radiographic images, which themselves are not clinical benefits. Additional supportive and confirmatory studies are required for validation.<\/span>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<div class=\"elementor-element elementor-element-368c5cbf elementor-widget elementor-widget-spacer\" data-id=\"368c5cbf\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-362172ee elementor-widget elementor-widget-heading\" data-id=\"362172ee\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-medium\">Recent Case Studies<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-6e6992c2 elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"6e6992c2\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-inner-column elementor-element elementor-element-2063d812\" data-id=\"2063d812\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-4bcba739 elementor-widget elementor-widget-image\" data-id=\"4bcba739\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"400\" height=\"400\" src=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/04\/\u91dd\u5291.png\" class=\"attachment-full size-full wp-image-2803\" alt=\"\" srcset=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/04\/\u91dd\u5291.png 400w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/04\/\u91dd\u5291-300x300.png 300w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/04\/\u91dd\u5291-150x150.png 150w\" sizes=\"(max-width: 400px) 100vw, 400px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-66 elementor-inner-column elementor-element elementor-element-1c0e1882\" data-id=\"1c0e1882\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-2ec5a88d elementor-widget elementor-widget-text-editor\" data-id=\"2ec5a88d\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<h6><span style=\"color: #0d344a;\"><strong>Spinraza<\/strong><\/span><\/h6><ul><li><span style=\"color: #0d344a;\">Spinraza is an orphan drug used to treat spinal muscular atrophy (SMA). SMA is a rare neurodegenerative disease that is usually detected in infants or young children and progressively worsens over time. It causes muscle weakness and atrophy, leading to impaired breathing, feeding, and mobility, and may result in death.<\/span><\/li><li><span style=\"color: #0d344a;\">The primary component of Spinraza is a nanoscale nucleic acid that increases the production of SMN protein, thereby helping to alleviate symptoms in SMA patients.<\/span><\/li><li><span style=\"color: #0d344a;\">In clinical trials, Spinraza has been shown to significantly improve motor function, respiratory and swallowing abilities, and overall quality of life for SMA patients.<\/span><\/li><li><span style=\"color: #0d344a;\">In August 2024, Taiwan&#8217;s Ministry of Health and Welfare expanded coverage and relaxed the reimbursement conditions for intrathecal injection drugs containing nusinersen and oral solutions containing risdiplam. The revisions include: (1) Expanding the original condition from &#8220;onset confirmed under the age of 3&#8221; to &#8220;onset confirmed under the age of 18.&#8221; (2) Removing the initial treatment condition requiring a RULM (Revised Upper Limb Module) score of \u226515. (3) Allowing a one-time switch to another drug if severe intolerant reactions occur after using nusinersen or risdiplam. The manufacturers agreed to a price reduction in conjunction with this expanded coverage, with the estimated annual drug cost per person being approximately NT$6.6 million. Around 250 patients are expected to benefit from this change, with an additional NT$1.9 billion allocated for drug expenses.<\/span><\/li><\/ul><p>&gt;&gt;<a href=\"https:\/\/www.mohw.gov.tw\/cp-6648-79655-1.html\">news<\/a><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-7301bf84 elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"7301bf84\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-inner-column elementor-element elementor-element-1da41408\" data-id=\"1da41408\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-2f8a572c elementor-widget elementor-widget-image\" data-id=\"2f8a572c\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"400\" height=\"400\" src=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/04\/\u53e3\u670d.png\" class=\"attachment-full size-full wp-image-2804\" alt=\"\" srcset=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/04\/\u53e3\u670d.png 400w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/04\/\u53e3\u670d-300x300.png 300w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/04\/\u53e3\u670d-150x150.png 150w\" sizes=\"(max-width: 400px) 100vw, 400px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-66 elementor-inner-column elementor-element elementor-element-4757df75\" data-id=\"4757df75\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-369104f1 elementor-widget elementor-widget-text-editor\" data-id=\"369104f1\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<h6><span style=\"color: #0d344a;\"><strong>Lumakras<\/strong><\/span><\/h6><div class=\"flex-1 overflow-hidden\"><div class=\"react-scroll-to-bottom--css-bbtpb-79elbk h-full dark:bg-gray-800\"><div class=\"react-scroll-to-bottom--css-bbtpb-1n7m0yu\"><div class=\"flex flex-col text-sm dark:bg-gray-800\"><div class=\"group w-full text-gray-800 dark:text-gray-100 border-b border-black\/10 dark:border-gray-900\/50 bg-gray-50 dark:bg-[#444654]\"><div class=\"flex p-4 gap-4 text-base md:gap-6 md:max-w-2xl lg:max-w-[38rem] xl:max-w-3xl md:py-6 lg:px-0 m-auto\"><div class=\"relative flex w-[calc(100%-50px)] flex-col gap-1 md:gap-3 lg:w-[calc(100%-115px)]\"><div class=\"flex flex-grow flex-col gap-3\"><div class=\"min-h-[20px] flex items-start overflow-x-auto whitespace-pre-wrap break-words flex-col gap-4\"><div class=\"markdown prose w-full break-words dark:prose-invert light\"><ul><li><span style=\"color: #0d344a;\">Lumakras is a small molecule KRAS G12C inhibitor developed by Amgen. It was approved by the U.S. FDA in 2021 for the treatment of advanced non-small cell lung cancer (NSCLC) patients with the KRAS G12C gene mutation.<\/span><\/li><li><span style=\"color: #0d344a;\">The KRAS G12C mutation is the most common mutation in non-small cell lung cancer, present in approximately 13% of NSCLC patients.<\/span><\/li><li><span style=\"color: #0d344a;\">Lumakras inhibits the growth and division of cells with the KRAS G12C mutation and can also prevent the spread of cancer cells.<\/span><\/li><li><span style=\"color: #0d344a;\">It has been granted orphan drug status by the U.S. FDA for the treatment of KRAS G12C-mutated advanced NSCLC.<\/span><\/li><li><span style=\"color: #0d344a;\">As of now, Lumakras has not been approved for reimbursement under the National Health Insurance in Taiwan. The out-of-pocket cost for a single-day highest dosage in the United States is approximately $700 USD (120mg * 8 tablets).<\/span><\/li><\/ul><\/div><\/div><\/div><div class=\"flex justify-between lg:block\">\u00a0<\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><div class=\"absolute bottom-0 left-0 w-full border-t md:border-t-0 dark:border-white\/20 md:border-transparent md:dark:border-transparent md:bg-vert-light-gradient bg-white dark:bg-gray-800 md:!bg-transparent dark:md:bg-vert-dark-gradient pt-2 md:pl-2 md:w-[calc(100%-.5rem)]\"><form class=\"stretch mx-2 flex flex-row gap-3 last:mb-2 md:mx-4 md:last:mb-6 lg:mx-auto lg:max-w-2xl xl:max-w-3xl\"><div class=\"relative flex h-full flex-1 items-stretch md:flex-col\" role=\"presentation\"><div class=\"\">\u00a0<\/div><\/div><\/form><\/div>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<div class=\"elementor-element elementor-element-73457547 elementor-widget elementor-widget-spacer\" data-id=\"73457547\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-6cb0270d elementor-widget elementor-widget-heading\" data-id=\"6cb0270d\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-medium\">Reference<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-397571d4 elementor-widget elementor-widget-text-editor\" data-id=\"397571d4\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<ol><li><a href=\"https:\/\/academicentrepreneurship.pubpub.org\/pub\/einr3b30\/release\/3\">https:\/\/academicentrepreneurship.pubpub.org\/pub\/einr3b30\/release\/3<\/a><\/li><li><a href=\"https:\/\/www.fda.gov\/industry\/developing-products-rare-diseases-conditions\/designating-orphan-product-drugs-and-biological-products\">https:\/\/www.fda.gov\/industry\/developing-products-rare-diseases-conditions\/designating-orphan-product-drugs-and-biological-products<\/a><\/li><li><a href=\"https:\/\/journals.plos.org\/plosone\/article?id=10.1371\/journal.pone.0140002\">https:\/\/journals.plos.org\/plosone\/article?id=10.1371\/journal.pone.0140002<\/a><\/li><li><a href=\"http:\/\/www.appliedclinicaltrialsonline.com\/pull-and-tug-orphan-drug-development\">http:\/\/www.appliedclinicaltrialsonline.com\/pull-and-tug-orphan-drug-development<\/a><\/li><li><a href=\"https:\/\/www.mohw.gov.tw\/cp-5271-71132-1.html\">https:\/\/www.mohw.gov.tw\/cp-5271-71132-1.html<\/a><\/li><li><a href=\"https:\/\/www.drugs.com\/price-guide\/lumakras\">https:\/\/www.drugs.com\/price-guide\/lumakras<\/a><\/li><li><a href=\"https:\/\/info.fda.gov.tw\/MLMS\/ShowFile.aspx?LicId=52028291&amp;Seq=001&amp;Type=9\">https:\/\/info.fda.gov.tw\/MLMS\/ShowFile.aspx?LicId=52028291&amp;Seq=001&amp;Type=9<\/a><\/li><li><a href=\"https:\/\/www.pwc.tw\/zh\/publications\/topic-bio\/assets\/a-rare-chance-for-reform.pdf\">https:\/\/www.pwc.tw\/zh\/publications\/topic-bio\/assets\/a-rare-chance-for-reform.pdf<\/a><\/li><\/ol>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-639f6b61 elementor-widget elementor-widget-spacer\" data-id=\"639f6b61\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-780e0426 elementor-widget elementor-widget-heading\" data-id=\"780e0426\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<span class=\"elementor-heading-title elementor-size-default\">This article is provided for informational purposes only regarding industry information. The development of new drugs involves lengthy timelines, high financial investments, and is not guaranteed to be successful. These factors may expose investors to risks, and therefore, investors should exercise caution and prudence when making investment decisions.<\/span>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-5e0d9ab elementor-section-stretched elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"5e0d9ab\" data-element_type=\"section\" data-settings=\"{&quot;stretch_section&quot;:&quot;section-stretched&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-2cf41d4\" data-id=\"2cf41d4\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-e61f652 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"e61f652\" data-element_type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.11.5 - 14-03-2023 *\/\n.elementor-widget-divider{--divider-border-style:none;--divider-border-width:1px;--divider-color:#2c2c2c;--divider-icon-size:20px;--divider-element-spacing:10px;--divider-pattern-height:24px;--divider-pattern-size:20px;--divider-pattern-url:none;--divider-pattern-repeat:repeat-x}.elementor-widget-divider .elementor-divider{display:flex}.elementor-widget-divider .elementor-divider__text{font-size:15px;line-height:1;max-width:95%}.elementor-widget-divider .elementor-divider__element{margin:0 var(--divider-element-spacing);flex-shrink:0}.elementor-widget-divider .elementor-icon{font-size:var(--divider-icon-size)}.elementor-widget-divider .elementor-divider-separator{display:flex;margin:0;direction:ltr}.elementor-widget-divider--view-line_icon .elementor-divider-separator,.elementor-widget-divider--view-line_text .elementor-divider-separator{align-items:center}.elementor-widget-divider--view-line_icon .elementor-divider-separator:after,.elementor-widget-divider--view-line_icon .elementor-divider-separator:before,.elementor-widget-divider--view-line_text .elementor-divider-separator:after,.elementor-widget-divider--view-line_text .elementor-divider-separator:before{display:block;content:\"\";border-bottom:0;flex-grow:1;border-top:var(--divider-border-width) var(--divider-border-style) var(--divider-color)}.elementor-widget-divider--element-align-left .elementor-divider .elementor-divider-separator>.elementor-divider__svg:first-of-type{flex-grow:0;flex-shrink:100}.elementor-widget-divider--element-align-left .elementor-divider-separator:before{content:none}.elementor-widget-divider--element-align-left .elementor-divider__element{margin-left:0}.elementor-widget-divider--element-align-right .elementor-divider .elementor-divider-separator>.elementor-divider__svg:last-of-type{flex-grow:0;flex-shrink:100}.elementor-widget-divider--element-align-right .elementor-divider-separator:after{content:none}.elementor-widget-divider--element-align-right .elementor-divider__element{margin-right:0}.elementor-widget-divider:not(.elementor-widget-divider--view-line_text):not(.elementor-widget-divider--view-line_icon) .elementor-divider-separator{border-top:var(--divider-border-width) var(--divider-border-style) var(--divider-color)}.elementor-widget-divider--separator-type-pattern{--divider-border-style:none}.elementor-widget-divider--separator-type-pattern.elementor-widget-divider--view-line .elementor-divider-separator,.elementor-widget-divider--separator-type-pattern:not(.elementor-widget-divider--view-line) .elementor-divider-separator:after,.elementor-widget-divider--separator-type-pattern:not(.elementor-widget-divider--view-line) .elementor-divider-separator:before,.elementor-widget-divider--separator-type-pattern:not([class*=elementor-widget-divider--view]) .elementor-divider-separator{width:100%;min-height:var(--divider-pattern-height);-webkit-mask-size:var(--divider-pattern-size) 100%;mask-size:var(--divider-pattern-size) 100%;-webkit-mask-repeat:var(--divider-pattern-repeat);mask-repeat:var(--divider-pattern-repeat);background-color:var(--divider-color);-webkit-mask-image:var(--divider-pattern-url);mask-image:var(--divider-pattern-url)}.elementor-widget-divider--no-spacing{--divider-pattern-size:auto}.elementor-widget-divider--bg-round{--divider-pattern-repeat:round}.rtl .elementor-widget-divider .elementor-divider__text{direction:rtl}.e-con-inner>.elementor-widget-divider,.e-con>.elementor-widget-divider{width:var(--container-widget-width,100%);--flex-grow:var(--container-widget-flex-grow)}<\/style>\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-bf8d98e elementor-widget elementor-widget-heading\" data-id=\"bf8d98e\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Development Pipeline<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-b131479 elementor-section-full_width elementor-section-stretched elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"b131479\" data-element_type=\"section\" data-settings=\"{&quot;stretch_section&quot;:&quot;section-stretched&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-narrow\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-2d4834b\" data-id=\"2d4834b\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-9b2a940 elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"9b2a940\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-c57196e\" data-id=\"c57196e\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-6be6a66 elementor-widget elementor-widget-image\" data-id=\"6be6a66\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"400\" height=\"400\" src=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/pipeline-1.png\" class=\"attachment-large size-large wp-image-1709\" alt=\"Pepline - EF-001\" srcset=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/pipeline-1.png 400w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/pipeline-1-300x300.png 300w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/pipeline-1-150x150.png 150w\" sizes=\"(max-width: 400px) 100vw, 400px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-cdaaa2c elementor-align-center e-transform e-transform elementor-widget elementor-widget-button\" data-id=\"cdaaa2c\" data-element_type=\"widget\" data-settings=\"{&quot;_transform_scale_effect&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:1.03,&quot;sizes&quot;:[]},&quot;_transform_scaleX_effect_hover&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:1.1,&quot;sizes&quot;:[]},&quot;_transform_scaleY_effect_hover&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:1.1,&quot;sizes&quot;:[]},&quot;_transform_scale_effect_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_scale_effect_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_scaleX_effect_hover_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_scaleX_effect_hover_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_scaleY_effect_hover_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_scaleY_effect_hover_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t<a href=\"https:\/\/www.efbiotech.com\/wordpress\/?page_id=1778\" class=\"elementor-button-link elementor-button elementor-size-sm\" role=\"button\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-text\">EF-001<\/span>\n\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-1c98237\" data-id=\"1c98237\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-2b5597f elementor-widget elementor-widget-image\" data-id=\"2b5597f\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"400\" height=\"400\" src=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/pepline-2.png\" class=\"attachment-large size-large wp-image-1710\" alt=\"Pepline - EF-009\" srcset=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/pepline-2.png 400w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/pepline-2-300x300.png 300w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/pepline-2-150x150.png 150w\" sizes=\"(max-width: 400px) 100vw, 400px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-58f8ccd elementor-align-center e-transform e-transform elementor-widget elementor-widget-button\" data-id=\"58f8ccd\" data-element_type=\"widget\" data-settings=\"{&quot;_transform_scale_effect&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:1.03,&quot;sizes&quot;:[]},&quot;_transform_scaleX_effect_hover&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:1.1,&quot;sizes&quot;:[]},&quot;_transform_scaleY_effect_hover&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:1.1,&quot;sizes&quot;:[]},&quot;_transform_scale_effect_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_scale_effect_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_scaleX_effect_hover_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_scaleX_effect_hover_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_scaleY_effect_hover_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_scaleY_effect_hover_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t<a href=\"https:\/\/www.efbiotech.com\/wordpress\/?page_id=1870\" class=\"elementor-button-link elementor-button elementor-size-sm\" role=\"button\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-text\">EF-009<\/span>\n\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-3b115c9\" data-id=\"3b115c9\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-34957aa elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"34957aa\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-fbea57e\" data-id=\"fbea57e\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-bcd1dce elementor-widget elementor-widget-image\" data-id=\"bcd1dce\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"400\" height=\"400\" src=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/pepline-3.png\" class=\"attachment-large size-large wp-image-1711\" alt=\"Pepline - HK-001\" srcset=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/pepline-3.png 400w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/pepline-3-300x300.png 300w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/pepline-3-150x150.png 150w\" sizes=\"(max-width: 400px) 100vw, 400px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-67e41c4 elementor-align-center e-transform e-transform elementor-widget elementor-widget-button\" data-id=\"67e41c4\" data-element_type=\"widget\" data-settings=\"{&quot;_transform_scale_effect&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:1.03,&quot;sizes&quot;:[]},&quot;_transform_scaleX_effect_hover&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:1.1,&quot;sizes&quot;:[]},&quot;_transform_scaleY_effect_hover&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:1.1,&quot;sizes&quot;:[]},&quot;_transform_scale_effect_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_scale_effect_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_scaleX_effect_hover_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_scaleX_effect_hover_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_scaleY_effect_hover_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_scaleY_effect_hover_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t<a href=\"https:\/\/www.efbiotech.com\/wordpress\/?page_id=3417\" class=\"elementor-button-link elementor-button elementor-size-sm\" role=\"button\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-text\">HK-001<\/span>\n\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-5a0e050\" data-id=\"5a0e050\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-5919fdf elementor-widget elementor-widget-image\" data-id=\"5919fdf\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"400\" height=\"400\" src=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/Pepline-4-1.png\" class=\"attachment-large size-large wp-image-1713\" alt=\"Pepline - EF-031\" srcset=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/Pepline-4-1.png 400w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/Pepline-4-1-300x300.png 300w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/Pepline-4-1-150x150.png 150w\" sizes=\"(max-width: 400px) 100vw, 400px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-0bf2d54 elementor-align-center e-transform e-transform elementor-widget elementor-widget-button\" data-id=\"0bf2d54\" data-element_type=\"widget\" data-settings=\"{&quot;_transform_scale_effect&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:1.03,&quot;sizes&quot;:[]},&quot;_transform_scaleX_effect_hover&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:1.1,&quot;sizes&quot;:[]},&quot;_transform_scaleY_effect_hover&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:1.1,&quot;sizes&quot;:[]},&quot;_transform_scale_effect_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_scale_effect_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_scaleX_effect_hover_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_scaleX_effect_hover_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_scaleY_effect_hover_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_scaleY_effect_hover_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t<a href=\"https:\/\/www.efbiotech.com\/wordpress\/?page_id=5401\" class=\"elementor-button-link elementor-button elementor-size-sm\" role=\"button\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-text\">EF-031<\/span>\n\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Orphan Drug When a r<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_sitemap_exclude":false,"_sitemap_priority":"","_sitemap_frequency":"","footnotes":""},"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.efbiotech.com\/wordpress\/index.php?rest_route=\/wp\/v2\/pages\/5808"}],"collection":[{"href":"https:\/\/www.efbiotech.com\/wordpress\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.efbiotech.com\/wordpress\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.efbiotech.com\/wordpress\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.efbiotech.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=5808"}],"version-history":[{"count":10,"href":"https:\/\/www.efbiotech.com\/wordpress\/index.php?rest_route=\/wp\/v2\/pages\/5808\/revisions"}],"predecessor-version":[{"id":10201,"href":"https:\/\/www.efbiotech.com\/wordpress\/index.php?rest_route=\/wp\/v2\/pages\/5808\/revisions\/10201"}],"wp:attachment":[{"href":"https:\/\/www.efbiotech.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=5808"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}