{"id":1778,"date":"2023-03-27T18:12:56","date_gmt":"2023-03-27T10:12:56","guid":{"rendered":"http:\/\/www.efbiotech.com\/wordpress\/?page_id=1778"},"modified":"2024-08-02T14:49:04","modified_gmt":"2024-08-02T06:49:04","slug":"elementor-1778","status":"publish","type":"page","link":"https:\/\/www.efbiotech.com\/wordpress\/?page_id=1778","title":{"rendered":"Cerebraca\u00ae Wafer\u200b | Brain Tumor Treatment"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"1778\" class=\"elementor elementor-1778\">\n\t\t\t\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-86f3af0 elementor-section-full_width elementor-section-stretched elementor-hidden-mobile elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"86f3af0\" data-element_type=\"section\" data-settings=\"{&quot;stretch_section&quot;:&quot;section-stretched&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-e0462c3\" data-id=\"e0462c3\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-43912a4 elementor-widget elementor-widget-image\" data-id=\"43912a4\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.11.5 - 14-03-2023 *\/\n.elementor-widget-image{text-align:center}.elementor-widget-image a{display:inline-block}.elementor-widget-image a img[src$=\".svg\"]{width:48px}.elementor-widget-image img{vertical-align:middle;display:inline-block}<\/style>\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"1366\" height=\"456\" src=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/06\/15.png\" class=\"attachment-full size-full wp-image-4084\" alt=\"\" srcset=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/06\/15.png 1366w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/06\/15-300x100.png 300w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/06\/15-1024x342.png 1024w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/06\/15-768x256.png 768w\" sizes=\"(max-width: 1366px) 100vw, 1366px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-0b99a55 elementor-widget elementor-widget-spacer\" data-id=\"0b99a55\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.11.5 - 14-03-2023 *\/\n.elementor-column .elementor-spacer-inner{height:var(--spacer-size)}.e-con{--container-widget-width:100%}.e-con-inner>.elementor-widget-spacer,.e-con>.elementor-widget-spacer{width:var(--container-widget-width,var(--spacer-size));--align-self:var(--container-widget-align-self,initial);--flex-shrink:0}.e-con-inner>.elementor-widget-spacer>.elementor-widget-container,.e-con-inner>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer,.e-con>.elementor-widget-spacer>.elementor-widget-container,.e-con>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer{height:100%}.e-con-inner>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer>.elementor-spacer-inner,.e-con>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer>.elementor-spacer-inner{height:var(--container-widget-height,var(--spacer-size))}<\/style>\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-0fe0c30 elementor-section-full_width elementor-section-stretched elementor-hidden-desktop elementor-hidden-tablet elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"0fe0c30\" data-element_type=\"section\" data-settings=\"{&quot;stretch_section&quot;:&quot;section-stretched&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-f40c426\" data-id=\"f40c426\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-e4dac23 elementor-widget-mobile__width-inherit elementor-widget elementor-widget-image\" data-id=\"e4dac23\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"1080\" height=\"1080\" src=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/06\/25.png\" class=\"attachment-full size-full wp-image-4876\" alt=\"\" srcset=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/06\/25.png 1080w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/06\/25-300x300.png 300w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/06\/25-1024x1024.png 1024w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/06\/25-150x150.png 150w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/06\/25-768x768.png 768w\" sizes=\"(max-width: 1080px) 100vw, 1080px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-70b1cec elementor-widget elementor-widget-spacer\" data-id=\"70b1cec\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-2be0310 elementor-section-stretched elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"2be0310\" data-element_type=\"section\" data-settings=\"{&quot;stretch_section&quot;:&quot;section-stretched&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-d1e1757\" data-id=\"d1e1757\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-68cc338 elementor-widget elementor-widget-heading\" data-id=\"68cc338\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.11.5 - 14-03-2023 *\/\n.elementor-heading-title{padding:0;margin:0;line-height:1}.elementor-widget-heading .elementor-heading-title[class*=elementor-size-]>a{color:inherit;font-size:inherit;line-height:inherit}.elementor-widget-heading .elementor-heading-title.elementor-size-small{font-size:15px}.elementor-widget-heading .elementor-heading-title.elementor-size-medium{font-size:19px}.elementor-widget-heading .elementor-heading-title.elementor-size-large{font-size:29px}.elementor-widget-heading .elementor-heading-title.elementor-size-xl{font-size:39px}.elementor-widget-heading .elementor-heading-title.elementor-size-xxl{font-size:59px}<\/style><h2 class=\"elementor-heading-title elementor-size-large\">Cerebraca\u00ae Wafer\u200b<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-b720056 elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"b720056\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-inner-column elementor-element elementor-element-29bf5f4\" data-id=\"29bf5f4\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-02ead42 elementor-widget elementor-widget-image\" data-id=\"02ead42\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"1200\" height=\"1200\" src=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2024\/03\/cerebraca-wafer-product-6.png\" class=\"attachment-full size-full wp-image-7231\" alt=\"CEREBRACA\u00ae WAFER\" srcset=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2024\/03\/cerebraca-wafer-product-6.png 1200w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2024\/03\/cerebraca-wafer-product-6-300x300.png 300w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2024\/03\/cerebraca-wafer-product-6-1024x1024.png 1024w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2024\/03\/cerebraca-wafer-product-6-150x150.png 150w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2024\/03\/cerebraca-wafer-product-6-768x768.png 768w\" sizes=\"(max-width: 1200px) 100vw, 1200px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-66 elementor-inner-column elementor-element elementor-element-4082919\" data-id=\"4082919\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-a20e792 elementor-widget elementor-widget-heading\" data-id=\"a20e792\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-medium\">Combining the small molecule active pharmaceutical ingredient EF-API-001 and the biodegradable polymer, Cerebraca\u00ae Wafer is capable of potent tumor cell killing, immune activation, and reducing chemotherapeutic drug resistance.<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b3a1f8f elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"b3a1f8f\" data-element_type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.11.5 - 14-03-2023 *\/\n.elementor-widget-divider{--divider-border-style:none;--divider-border-width:1px;--divider-color:#2c2c2c;--divider-icon-size:20px;--divider-element-spacing:10px;--divider-pattern-height:24px;--divider-pattern-size:20px;--divider-pattern-url:none;--divider-pattern-repeat:repeat-x}.elementor-widget-divider .elementor-divider{display:flex}.elementor-widget-divider .elementor-divider__text{font-size:15px;line-height:1;max-width:95%}.elementor-widget-divider .elementor-divider__element{margin:0 var(--divider-element-spacing);flex-shrink:0}.elementor-widget-divider .elementor-icon{font-size:var(--divider-icon-size)}.elementor-widget-divider .elementor-divider-separator{display:flex;margin:0;direction:ltr}.elementor-widget-divider--view-line_icon .elementor-divider-separator,.elementor-widget-divider--view-line_text .elementor-divider-separator{align-items:center}.elementor-widget-divider--view-line_icon .elementor-divider-separator:after,.elementor-widget-divider--view-line_icon .elementor-divider-separator:before,.elementor-widget-divider--view-line_text .elementor-divider-separator:after,.elementor-widget-divider--view-line_text .elementor-divider-separator:before{display:block;content:\"\";border-bottom:0;flex-grow:1;border-top:var(--divider-border-width) var(--divider-border-style) var(--divider-color)}.elementor-widget-divider--element-align-left .elementor-divider .elementor-divider-separator>.elementor-divider__svg:first-of-type{flex-grow:0;flex-shrink:100}.elementor-widget-divider--element-align-left .elementor-divider-separator:before{content:none}.elementor-widget-divider--element-align-left .elementor-divider__element{margin-left:0}.elementor-widget-divider--element-align-right .elementor-divider .elementor-divider-separator>.elementor-divider__svg:last-of-type{flex-grow:0;flex-shrink:100}.elementor-widget-divider--element-align-right .elementor-divider-separator:after{content:none}.elementor-widget-divider--element-align-right .elementor-divider__element{margin-right:0}.elementor-widget-divider:not(.elementor-widget-divider--view-line_text):not(.elementor-widget-divider--view-line_icon) .elementor-divider-separator{border-top:var(--divider-border-width) var(--divider-border-style) var(--divider-color)}.elementor-widget-divider--separator-type-pattern{--divider-border-style:none}.elementor-widget-divider--separator-type-pattern.elementor-widget-divider--view-line .elementor-divider-separator,.elementor-widget-divider--separator-type-pattern:not(.elementor-widget-divider--view-line) .elementor-divider-separator:after,.elementor-widget-divider--separator-type-pattern:not(.elementor-widget-divider--view-line) .elementor-divider-separator:before,.elementor-widget-divider--separator-type-pattern:not([class*=elementor-widget-divider--view]) .elementor-divider-separator{width:100%;min-height:var(--divider-pattern-height);-webkit-mask-size:var(--divider-pattern-size) 100%;mask-size:var(--divider-pattern-size) 100%;-webkit-mask-repeat:var(--divider-pattern-repeat);mask-repeat:var(--divider-pattern-repeat);background-color:var(--divider-color);-webkit-mask-image:var(--divider-pattern-url);mask-image:var(--divider-pattern-url)}.elementor-widget-divider--no-spacing{--divider-pattern-size:auto}.elementor-widget-divider--bg-round{--divider-pattern-repeat:round}.rtl .elementor-widget-divider .elementor-divider__text{direction:rtl}.e-con-inner>.elementor-widget-divider,.e-con>.elementor-widget-divider{width:var(--container-widget-width,100%);--flex-grow:var(--container-widget-flex-grow)}<\/style>\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-73e109b elementor-widget elementor-widget-text-editor\" data-id=\"73e109b\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.11.5 - 14-03-2023 *\/\n.elementor-widget-text-editor.elementor-drop-cap-view-stacked .elementor-drop-cap{background-color:#818a91;color:#fff}.elementor-widget-text-editor.elementor-drop-cap-view-framed .elementor-drop-cap{color:#818a91;border:3px solid;background-color:transparent}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap{margin-top:8px}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap-letter{width:1em;height:1em}.elementor-widget-text-editor .elementor-drop-cap{float:left;text-align:center;line-height:1;font-size:50px}.elementor-widget-text-editor .elementor-drop-cap-letter{display:inline-block}<\/style>\t\t\t\t<ul><li><span style=\"color: #ff914d;\"><b>Cerebraca<\/b>\u00ae<b> Wafer <\/b><\/span><span style=\"color: #0d344a;\">is a therapeutic drug wafer that can be used to treat highly malignant glioblastoma (malignant brain cancer). It can be directly implanted into the brain and slowly releases drugs at a high concentration, high penetration, and long duration for about 1 month, exerting a multi-target effect that helps to treat cancer and make cancer cells more susceptible to chemotherapy or immune cell killing.<\/span><\/li><li><span style=\"color: #0d344a;\">Glioblastoma multiforme (GBM) is a highly malignant primary brain tumor that can <strong>grow up to 16 times<\/strong> its original size within a month. It has a high rate of recurrence after surgical resection, and there are currently <strong>no effective treatment options available<\/strong>.<\/span><\/li><li><span style=\"color: #ff914d;\"><b><span style=\"color: #0d344a;\">EF-API-001, <\/span><\/b><\/span><span style=\"color: #0d344a;\">the small molecule active pharmarceutical ingredient\u00a0 in <\/span><span style=\"color: #ff914d;\"><b>Cerebraca<\/b>\u00ae<b> Wafer<\/b><\/span><span style=\"color: #0d344a;\">, has the following characteristics:<\/span><ul><li><span style=\"color: #0d344a;\"><strong>Targeting\u00a0Axl-1 receptor tyrosine kinase:<\/strong> effectively inhibits the growth and metastasis of brain tumor stem cells.<\/span><\/li><li><span style=\"color: #0d344a;\"><strong>Inhibiting the PD-L1 immune checkpoint: <\/strong>reduces the immune suppressive nature of the tumor microenvironment, thus preserving the activity of immune cells to kill tumor cells.\u00a0<\/span><\/li><li><span style=\"color: #0d344a;\"><strong>Inhibition of MGMT DNA repair enzyme:<\/strong> overcomes resistance to Temozolomide (chemotherapy drug) and enables cancer cells to be killed again by chemotherapy.<\/span><\/li><\/ul><\/li><li><span style=\"color: #ff914d;\"><b>Cerebraca<\/b>\u00ae<b> Wafer<\/b><\/span><span style=\"color: #0d344a;\">, its small molecule active ingredient and biodegradable polymer are all manufactured by internationally renowned PIC\/S GMP pharmaceutical companies in Taiwan to ensure high quality and reliable aseptic manufacturing processes.<\/span><\/li><\/ul>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<div class=\"elementor-element elementor-element-4c94749 elementor-widget elementor-widget-spacer\" data-id=\"4c94749\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-2cc5c9d elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"2cc5c9d\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-wide\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-14e1829\" data-id=\"14e1829\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-8ba2eb6 elementor-widget elementor-widget-heading\" data-id=\"8ba2eb6\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-medium\">A Phase I\/IIa Study of Cerebraca Wafer Plus Adjuvant Temozolomide (TMZ) in Patients With Recurrent High Grade Glioma<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4b8c5e8 elementor-widget elementor-widget-text-editor\" data-id=\"4b8c5e8\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p style=\"text-align: center;\"><a href=\"https:\/\/clinicaltrials.gov\/ct2\/show\/NCT03234595\">ClinicalTrials.gov Identifier:\u00a0NCT03234595<\/a><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-587bb18 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"587bb18\" data-element_type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-dfac2a1 elementor-widget elementor-widget-text-editor\" data-id=\"dfac2a1\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<ul>\n<li>\n<p><span style=\"color: #ff914d;\"><b>Phaes I<\/b><\/span><\/p>\n<ul>\n<li><span style=\"color: #0d344a;\">In August 2020, the Taiwan Phase I clinical trial was completed<\/span><\/li>\n<li><span style=\"color: #0d344a;\">No adverse events related to the investigational drug were found throughout the trial<\/span><\/li>\n<li><span style=\"color: #0d344a;\">In Cohort IV, which received high dosage:&nbsp;<\/span>\n<ul>\n<li><span style=\"color: #0d344a;\">the median overall survival (OS) has reached 26.2 months (updated on July 2022), compared to existing strategies such as Gliadel\u00ae wafer (6.4 months), Temodar (5.8 months), or Avastin (9.4 months)<\/span><\/li>\n<li><span style=\"color: #0d344a;\">The progression-free survival (PFS) rate at 6 months was 100%.<\/span><\/li>\n<\/ul>\n<\/li>\n<li><span style=\"color: #0d344a;\"><em>Cancers<\/em>&nbsp;<b>2022<\/b>,&nbsp;<em>14<\/em>(4), 1051;<\/span>&nbsp;<a href=\"https:\/\/doi.org\/10.3390\/cancers14041051\">https:\/\/doi.org\/10.3390\/cancers14041051<\/a><\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<ul>\n<li><strong><span style=\"color: #ff914d;\">Phase IIa<\/span><\/strong>\n<ul>\n<li><span style=\"color: #0d344a;\">In October 2022, completed enrollment for the Taiwan phase IIa clinical trial<\/span><\/li>\n<li><span style=\"color: #0d344a;\">CSR will be finalized by end of March in 2024.<\/span><\/li>\n<\/ul>\n<\/li>\n<\/ul>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-ebf3855 elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"ebf3855\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-bd029f8\" data-id=\"bd029f8\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-2afbb0f elementor-widget__width-initial elementor-widget elementor-widget-heading\" data-id=\"2afbb0f\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-medium\">Cerebraca\u00ae Wafer is More Effective in Overcome Cancer Stem Cells in Recurrent GBM<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4eaf45b elementor-widget elementor-widget-text-editor\" data-id=\"4eaf45b\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<ul><li><span style=\"color: #0d344a;\">As below Table shows, seven out of eight primary glioma lines acquired in this clinical trial revealed high expression of the cancer stem cell markers, CD133 and SOX2, suggesting that tumor recurrence presents high cancer stem cell generation. <\/span><\/li><li><span style=\"color: #0d344a;\">The IC<sub>50<\/sub> of BCNU (active ingredient in Gliadel Wafer) in T1, a non-tumor stem cell line, was approximately 1200 \u00b5M. We further showed that GBM cells with high stem cell marker expression had higher IC<sub>50<\/sub> when treated with BCNU (\u22651600 \u00b5M). This result possibly correlates to the limited therapeutic effects of the BCNUloaded Gliadel wafer.<\/span><\/li><li><span style=\"color: #0d344a;\"> However, the IC<sub>50<\/sub> of BP (EF-API-001) in patient-derived primary glioma cell lines was lower than that of BCNU, indicating that the API of the Cerebraca wafer was more efficient than that of the Gliadel wafer. We further demonstrated that the IC<sub>50<\/sub> of BP was around four times lower than that of the BCNU.<\/span><\/li><li><span style=\"color: #0d344a;\"> Additionally, the difference in drug loading between the Cerebraca and Gliadel wafers was almost 10-fold (75 vs. 7.7 mg per wafer), which makes the cancer cell killing possible<\/span><\/li><li><span style=\"color: #0d344a;\">For more detailed information, please refer to <em>Cancers<\/em>\u00a0<b>2022<\/b>,\u00a0<em>14<\/em>(4), 1051;<\/span>\u00a0<a href=\"https:\/\/doi.org\/10.3390\/cancers14041051\">https:\/\/doi.org\/10.3390\/cancers14041051<\/a><\/li><\/ul>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<div class=\"elementor-element elementor-element-c8e3535 elementor-widget elementor-widget-image\" data-id=\"c8e3535\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"1366\" height=\"768\" src=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/05\/BP.png\" class=\"attachment-full size-full wp-image-3636\" alt=\"Synergistic effect of BP in patient-derived primary glioblastoma cell lines\" srcset=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/05\/BP.png 1366w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/05\/BP-300x169.png 300w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/05\/BP-1024x576.png 1024w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/05\/BP-768x432.png 768w\" sizes=\"(max-width: 1366px) 100vw, 1366px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5a57c5b elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"5a57c5b\" data-element_type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-70cefb3 elementor-widget elementor-widget-spacer\" data-id=\"70cefb3\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-14db669 elementor-widget elementor-widget-text-editor\" data-id=\"14db669\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<h6><span style=\"color: #ff914d;\"><b>Curing<\/b> <b>Rare Cancers<\/b><\/span><\/h6><ul><li><span style=\"color: #0d344a;\"><b><span style=\"color: #ff914d;\">Rare Cancers are a subset of orphan diseases <\/span><\/b>that affect so few people that trying to cure them makes little economic sense without public incentives and special regulatory benefits.<\/span><\/li><li><span style=\"color: #0d344a;\"><b><span style=\"color: #ff914d;\">Our mission is to develop orphan drugs to treat rare cancers<\/span> <\/b>chosen for their low probability of survival due to the lack of effective treatments, the presence of few competitors offering objectively inferior products based on key medical metrics, and the possibility of rapidly gaining market share via licensing agreements with global pharma partners.<\/span><\/li><\/ul>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-dc4a965 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"dc4a965\" data-element_type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b1f360b elementor-widget elementor-widget-spacer\" data-id=\"b1f360b\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1cdf33e elementor-widget elementor-widget-text-editor\" data-id=\"1cdf33e\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<h6><span style=\"color: #ff914d;\"><b>Glioblastoma (GBM)<\/b><\/span><\/h6><ul><li><p>The most common and lethal primary brain tumor Glioblastoma (GBM) is highly resistant to conventional radiotherapy and chemotherapy and cannot be effectively controlled by surgical resection. As recurrence is\u00a0 inevitable and progresses rapidly, GBM is considered essentially incurable. Survival rate is low and median life expectancy is 6 months after relapse.<\/p><\/li><li><p style=\"font-variant-ligatures: normal; font-variant-caps: normal; font-family: Arial, sans-serif; font-size: 14px; font-style: normal; font-weight: 400; color: #7a7a7a; text-align: start;\"><span style=\"font-size: 14px; color: #ff914d;\"><span style=\"font-weight: bold;\">Glioblastoma (GBM)\u00a0<\/span><\/span>is the most common and lethal primary brain tumor that is highly resistant to conventional radiotherapy and chemotherapy, which cannot be effectively controlled by surgical resection. Recurrence is\u00a0 inevitable and progresses rapidly, rendering GBM essentially incurable. Survival rate is low, median is half a year after relapse.\u00a0\u00a0<\/p><\/li><li><p style=\"font-variant-ligatures: normal; font-variant-caps: normal; font-family: Arial, sans-serif; font-size: 14px; font-style: normal; font-weight: 400; color: #7a7a7a; text-align: start;\"><span style=\"font-family: Arial, sans-serif; font-size: 14px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; color: #ff914d;\"><span style=\"font-weight: bold;\">A great challenge in current therapies\u00a0<\/span><\/span><span style=\"font-family: Arial, sans-serif; font-size: 14px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400;\">lies in delivering chemotherapeutic agents effectively to the tumor location in the presence of blood-brain barrier (BBB) and blood-brain tumor barrier (BBTB), a hurdle that is reducing the efficacy of anti-tumor drugs in GBM therapy.<\/span><\/p><\/li><\/ul>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-8f0b38e elementor-widget elementor-widget-spacer\" data-id=\"8f0b38e\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-6a16c57 elementor-widget elementor-widget-text-editor\" data-id=\"6a16c57\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<h6><span style=\"color: #ff914d;\"><b>Why Target Glioblastoma Multiforme (GBM)<\/b><\/span><\/h6><ul><li><p><span style=\"color: #ff914d;\"><strong>There have been no new advancements in Glioblastoma Multiforme (GBM) treatment for nearly 20 years<\/strong><\/span><span style=\"color: #0d344a;\">, compared to other cancer treatments such as lung cancer, where over 30 drugs have been introduced in the past two decades.<\/span><\/p><\/li><li><p><span style=\"color: #0d344a;\">This highlights the difficulties and challenges faced globally in the treatment of brain cancer, which is a primary reason for our active involvement in this field.<\/span><\/p><\/li><\/ul>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-e75c0bc elementor-widget elementor-widget-image\" data-id=\"e75c0bc\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"800\" height=\"450\" src=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2024\/03\/No-New-Advancements-in-GBM-Treatment-for-20-Years-1024x576.png\" class=\"attachment-large size-large wp-image-7060\" alt=\"No New Advancements in GBM Treatment for 20 Years\" srcset=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2024\/03\/No-New-Advancements-in-GBM-Treatment-for-20-Years-1024x576.png 1024w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2024\/03\/No-New-Advancements-in-GBM-Treatment-for-20-Years-300x169.png 300w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2024\/03\/No-New-Advancements-in-GBM-Treatment-for-20-Years-768x432.png 768w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2024\/03\/No-New-Advancements-in-GBM-Treatment-for-20-Years.png 1366w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-29adb3a elementor-widget elementor-widget-spacer\" data-id=\"29adb3a\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-9aa3fc0 elementor-widget elementor-widget-heading\" data-id=\"9aa3fc0\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-medium\">Our Innovative Approach<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-e997e37 elementor-section-height-min-height elementor-section-boxed elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"e997e37\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-narrow\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-5084779\" data-id=\"5084779\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-3839685 elementor-widget elementor-widget-image\" data-id=\"3839685\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"150\" height=\"150\" src=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/icon-1-150x150.png\" class=\"attachment-thumbnail size-thumbnail wp-image-1785\" alt=\"\" srcset=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/icon-1-150x150.png 150w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/icon-1-300x300.png 300w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/icon-1.png 709w\" sizes=\"(max-width: 150px) 100vw, 150px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-c57f14c\" data-id=\"c57f14c\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-ef92b93 elementor-widget elementor-widget-text-editor\" data-id=\"ef92b93\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><span style=\"color: #0d344a;\"><b>Harness the Power of the Human <\/b><b>I<\/b><b>mmune <\/b><b>S<\/b><b>ystem<\/b><\/span><\/p>\n<p><span style=\"color: #0d344a;\">We seeks to identify and develop active compounds with the ability to amplify the body\u2019s natural defense across many metrics, both by fortifying the patients\u2019 immune system and weakening the disease to increase its vulnerability to medical treatments.<\/span><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-ddd6b90 elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"ddd6b90\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-narrow\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-950d815\" data-id=\"950d815\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-e6b3595 elementor-widget elementor-widget-image\" data-id=\"e6b3595\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"150\" height=\"150\" src=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/icon-2-150x150.png\" class=\"attachment-thumbnail size-thumbnail wp-image-1786\" alt=\"\" srcset=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/icon-2-150x150.png 150w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/icon-2-300x300.png 300w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/icon-2.png 709w\" sizes=\"(max-width: 150px) 100vw, 150px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-02e28bc\" data-id=\"02e28bc\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-069f8b7 elementor-widget elementor-widget-text-editor\" data-id=\"069f8b7\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><span style=\"color: #0d344a;\"><b>Use Small Molecules Drugs as Our Key Therapeutics<\/b><\/span><\/p><p><span style=\"color: #0d344a;\">Given their relatively low molecular weight, simple chemical structures, more predictable pharmacokinetics and pharmacodynamics,\u00a0 small molecule drugs not only have superior safety profiles, but they can pass through cell membranes to reach intracellular targets and be formulated in many forms.<\/span><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-37b57be elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"37b57be\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-narrow\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-bc75c3b\" data-id=\"bc75c3b\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-a395a6f elementor-widget elementor-widget-image\" data-id=\"a395a6f\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"150\" height=\"150\" src=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/icon-3-150x150.png\" class=\"attachment-thumbnail size-thumbnail wp-image-1787\" alt=\"\" srcset=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/icon-3-150x150.png 150w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/icon-3-300x300.png 300w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/icon-3.png 709w\" sizes=\"(max-width: 150px) 100vw, 150px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-81cac01\" data-id=\"81cac01\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-13df96d elementor-widget elementor-widget-text-editor\" data-id=\"13df96d\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><span style=\"color: #0d344a;\"><b>Improving Efficacy with Targeted Drug Delivery<\/b><\/span><\/p><p><span style=\"color: #0d344a;\">We use targeted drug delivery platforms to improve the efficacy of our products with options like slow-released local delivery system, systemic drug delivery system, dripping pill formulation, dermal application formulation and injectable formulation.<\/span><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<div class=\"elementor-element elementor-element-547fa3e elementor-widget elementor-widget-spacer\" data-id=\"547fa3e\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c690938 elementor-widget elementor-widget-heading\" data-id=\"c690938\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-medium\">Product Profile<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-4c9de66 elementor-section-height-min-height elementor-section-boxed elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"4c9de66\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-inner-column elementor-element elementor-element-4d2fd52\" data-id=\"4d2fd52\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-7b2b163 elementor-widget elementor-widget-text-editor\" data-id=\"7b2b163\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p class=\"elementor-heading-title elementor-size-medium elementor-inline-editing pen\" style=\"font-variant-ligatures: normal; font-variant-caps: normal; font-family: var( --e-global-typography-primary-font-family ), Sans-serif; font-size: 19px; font-style: normal; font-weight: var( --e-global-typography-primary-font-weight ); color: #0d344a; text-align: center;\" data-elementor-setting-key=\"title\" data-pen-placeholder=\"\u5728\u6b64\u8f38\u5165...\"><span style=\"color: #ffffff;\">Product Name<\/span><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-66 elementor-inner-column elementor-element elementor-element-f1aceda\" data-id=\"f1aceda\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-82e2467 elementor-widget elementor-widget-text-editor\" data-id=\"82e2467\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p class=\"elementor-heading-title elementor-size-medium elementor-inline-editing pen\" style=\"font-variant-ligatures: normal; font-variant-caps: normal; font-family: var( --e-global-typography-primary-font-family ), Sans-serif; font-size: 19px; font-style: normal; font-weight: var( --e-global-typography-primary-font-weight ); color: #0d344a; text-align: left;\" data-elementor-setting-key=\"title\" data-pen-placeholder=\"\u5728\u6b64\u8f38\u5165...\">Cerebraca\u00ae Wafer<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-ea76d3e elementor-section-height-min-height elementor-section-boxed elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"ea76d3e\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-inner-column elementor-element elementor-element-846c301\" data-id=\"846c301\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-0a7548c elementor-widget elementor-widget-text-editor\" data-id=\"0a7548c\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p class=\"elementor-heading-title elementor-size-medium elementor-inline-editing pen\" style=\"font-variant-ligatures: normal; font-variant-caps: normal; font-family: var( --e-global-typography-primary-font-family ), Sans-serif; font-size: 19px; font-style: normal; font-weight: var( --e-global-typography-primary-font-weight ); color: #0d344a; text-align: center;\" data-elementor-setting-key=\"title\" data-pen-placeholder=\"\u5728\u6b64\u8f38\u5165...\"><span style=\"color: #ffffff;\">Disease<\/span><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-66 elementor-inner-column elementor-element elementor-element-524d15b\" data-id=\"524d15b\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-9d10fb8 elementor-widget elementor-widget-text-editor\" data-id=\"9d10fb8\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p data-elementor-setting-key=\"title\" data-pen-placeholder=\"\u5728\u6b64\u8f38\u5165...\"><span style=\"color: #0d344a;\">Brain\u00a0tumor\u00a0(glioma and meningioma)<\/span><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-1aca344 elementor-section-height-min-height elementor-section-boxed elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"1aca344\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-inner-column elementor-element elementor-element-ddf3bab\" data-id=\"ddf3bab\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-cbfc2e1 elementor-widget elementor-widget-text-editor\" data-id=\"cbfc2e1\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p class=\"elementor-heading-title elementor-size-medium elementor-inline-editing pen\" style=\"font-variant-ligatures: normal; font-variant-caps: normal; font-family: var( --e-global-typography-primary-font-family ), Sans-serif; font-size: 19px; font-style: normal; font-weight: var( --e-global-typography-primary-font-weight ); color: #0d344a; text-align: center;\" data-elementor-setting-key=\"title\" data-pen-placeholder=\"\u5728\u6b64\u8f38\u5165...\"><span style=\"color: #ffffff;\">Target Market\u200b<\/span><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-66 elementor-inner-column elementor-element elementor-element-9912371\" data-id=\"9912371\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-357a08c elementor-widget elementor-widget-text-editor\" data-id=\"357a08c\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p data-elementor-setting-key=\"title\" data-pen-placeholder=\"\u5728\u6b64\u8f38\u5165...\"><span style=\"color: #0d344a;\">North America, Europe, Asia, China, Japan, others<\/span><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-bad4eb1 elementor-section-height-min-height elementor-section-boxed elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"bad4eb1\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-inner-column elementor-element elementor-element-6361515\" data-id=\"6361515\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-390f97c elementor-widget elementor-widget-text-editor\" data-id=\"390f97c\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p class=\"elementor-heading-title elementor-size-medium elementor-inline-editing pen\" style=\"font-variant-ligatures: normal; font-variant-caps: normal; font-family: var( --e-global-typography-primary-font-family ), Sans-serif; font-size: 19px; font-style: normal; font-weight: var( --e-global-typography-primary-font-weight ); color: #0d344a; text-align: center;\" data-elementor-setting-key=\"title\" data-pen-placeholder=\"\u5728\u6b64\u8f38\u5165...\"><span style=\"color: #ffffff;\">Market Size\u200b<\/span><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-66 elementor-inner-column elementor-element elementor-element-10fc949\" data-id=\"10fc949\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-b5eb913 elementor-widget elementor-widget-text-editor\" data-id=\"b5eb913\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p data-elementor-setting-key=\"title\" data-pen-placeholder=\"\u5728\u6b64\u8f38\u5165...\"><span style=\"font-family: Arial, sans-serif; font-size: 14px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; color: #0d344a;\">US market worth around <strong>USD 1.714 billion*<\/strong><\/span><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-7ee082a elementor-section-height-min-height elementor-section-boxed elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"7ee082a\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-inner-column elementor-element elementor-element-dca05a7\" data-id=\"dca05a7\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-24009d0 elementor-widget elementor-widget-text-editor\" data-id=\"24009d0\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p class=\"elementor-heading-title elementor-size-medium elementor-inline-editing pen\" style=\"font-variant-ligatures: normal; font-variant-caps: normal; font-family: var( --e-global-typography-primary-font-family ), Sans-serif; font-size: 19px; font-style: normal; font-weight: var( --e-global-typography-primary-font-weight ); color: #0d344a; text-align: center;\" data-elementor-setting-key=\"title\" data-pen-placeholder=\"\u5728\u6b64\u8f38\u5165...\"><span style=\"color: #ffffff;\">Competition Size\u200b<\/span><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-66 elementor-inner-column elementor-element elementor-element-145e01d\" data-id=\"145e01d\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-ab75153 elementor-widget elementor-widget-text-editor\" data-id=\"ab75153\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p data-elementor-setting-key=\"title\" data-pen-placeholder=\"\u5728\u6b64\u8f38\u5165...\"><span style=\"font-family: Arial, sans-serif; font-size: 14px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; color: #0d344a;\">Patents on much less effective Gliadel\u00ae wafer and TMZ have expired.<\/span><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-311128b elementor-section-height-min-height elementor-section-boxed elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"311128b\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-inner-column elementor-element elementor-element-1a2d5bd\" data-id=\"1a2d5bd\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-5f35b0e elementor-widget elementor-widget-text-editor\" data-id=\"5f35b0e\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p class=\"elementor-heading-title elementor-size-medium elementor-inline-editing pen\" style=\"font-variant-ligatures: normal; font-variant-caps: normal; font-family: var( --e-global-typography-primary-font-family ), Sans-serif; font-size: 19px; font-style: normal; font-weight: var( --e-global-typography-primary-font-weight ); color: #0d344a; text-align: center;\" data-elementor-setting-key=\"title\" data-pen-placeholder=\"\u5728\u6b64\u8f38\u5165...\"><span style=\"color: #ffffff;\">Objective Size\u200b<\/span><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-66 elementor-inner-column elementor-element elementor-element-a4309dc\" data-id=\"a4309dc\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-63bd613 elementor-widget elementor-widget-text-editor\" data-id=\"63bd613\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p data-elementor-setting-key=\"title\" data-pen-placeholder=\"\u5728\u6b64\u8f38\u5165...\"><span style=\"color: #0d344a;\"><span style=\"font-family: Arial, sans-serif; font-size: 14px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400;\">Best-in-class surgical combination therapy capturing a\u00a0<\/span><span style=\"font-weight: bold; font-family: Arial, sans-serif; font-size: 14px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal;\">15% market share\u00a0<\/span><span style=\"font-family: Arial, sans-serif; font-size: 14px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400;\">from both the chemotherapy and the immunotherapy market.<\/span><\/span><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<div class=\"elementor-element elementor-element-15ac4db elementor-widget elementor-widget-text-editor\" data-id=\"15ac4db\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><span style=\"color: #0d344a;\">*The global brain tumor drug market was approximately $2.31 billion in 2021 and is expected to increase to $4.43 billion by 2029, reflecting a compound annual growth rate, or CAGR (<\/span>compound annual growth rate<span style=\"color: #0d344a;\">), of 9.0% over that period. (<i>Fortune Business Insight<\/i> <i>(2021-2029)<\/i>)<\/span><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-af2ac75 elementor-widget elementor-widget-spacer\" data-id=\"af2ac75\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4f9454e elementor-widget elementor-widget-heading\" data-id=\"4f9454e\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-medium\">How Does Cerebraca\u00ae Wafer Work?\n<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-430b70d elementor-widget elementor-widget-video\" data-id=\"430b70d\" data-element_type=\"widget\" data-settings=\"{&quot;youtube_url&quot;:&quot;https:\\\/\\\/youtu.be\\\/ShhAyxTAcXk&quot;,&quot;loop&quot;:&quot;yes&quot;,&quot;video_type&quot;:&quot;youtube&quot;}\" data-widget_type=\"video.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.11.5 - 14-03-2023 *\/\n.elementor-widget-video .elementor-widget-container{overflow:hidden;transform:translateZ(0)}.elementor-widget-video .elementor-wrapper iframe,.elementor-widget-video .elementor-wrapper video{height:100%;width:100%;display:flex;border:none;background-color:#000}.elementor-widget-video .elementor-open-inline .elementor-custom-embed-image-overlay{position:absolute;top:0;left:0;width:100%;height:100%;background-size:cover;background-position:50%}.elementor-widget-video .elementor-custom-embed-image-overlay{cursor:pointer;text-align:center}.elementor-widget-video .elementor-custom-embed-image-overlay:hover .elementor-custom-embed-play i{opacity:1}.elementor-widget-video .elementor-custom-embed-image-overlay img{display:block;width:100%}.elementor-widget-video .e-hosted-video .elementor-video{-o-object-fit:cover;object-fit:cover}.e-con-inner>.elementor-widget-video,.e-con>.elementor-widget-video{width:var(--container-widget-width);--flex-grow:var(--container-widget-flex-grow)}<\/style>\t\t<div class=\"elementor-wrapper elementor-open-inline\">\n\t\t\t<div class=\"elementor-video\"><\/div>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-641722c elementor-widget elementor-widget-image\" data-id=\"641722c\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"800\" height=\"450\" src=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/CW-works-1024x576.png\" class=\"attachment-large size-large wp-image-1822\" alt=\"\" srcset=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/CW-works-1024x576.png 1024w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/CW-works-300x169.png 300w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/CW-works-768x432.png 768w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/CW-works.png 1366w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-a4ab673 elementor-widget elementor-widget-text-editor\" data-id=\"a4ab673\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><strong><span style=\"color: #0d344a;\">After surgical resection of recurrent brain tumors, Cerebraca\u00ae Wafer (implanted tablets) will be implanted during the operation. The tablets will slowly decompose and release small-molecule targeted drugs directly into the tumor, so sufficient drug concentration can be achieved locally in the lesion,\u00a0 killing cancer cells that cannot be completely removed by surgery without damaging other tissues.<\/span><\/strong><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-fdf32e1 elementor-widget elementor-widget-spacer\" data-id=\"fdf32e1\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1a1f187 elementor-widget elementor-widget-heading\" data-id=\"1a1f187\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-medium\">Why Cerebraca\u00ae Wafer Does It Better\non Curing GBM?\n<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-65554f4 elementor-widget elementor-widget-heading\" data-id=\"65554f4\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h6 class=\"elementor-heading-title elementor-size-default\">\u25a0 US FDA Orphan Drug Certification<\/h6>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5c83a2e elementor-widget elementor-widget-text-editor\" data-id=\"5c83a2e\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><span style=\"color: #0d344a;\">The protection and preferential measures are granted under the Orphan Drug Development Act.<\/span><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5e8ce1b elementor-widget elementor-widget-heading\" data-id=\"5e8ce1b\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h6 class=\"elementor-heading-title elementor-size-default\">\u25a0 Providing Longer Life Expectancy<\/h6>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-dbebb5c elementor-widget elementor-widget-text-editor\" data-id=\"dbebb5c\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><span style=\"color: #0d344a;\">Phase I clinical trial results shows median overall survival of patients who received the highest dose exceeded 2 years, and one patient still lives a normal life 3 years in the treatment.<\/span><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5acce8f elementor-widget elementor-widget-heading\" data-id=\"5acce8f\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h6 class=\"elementor-heading-title elementor-size-default\">\u25a0 Low-toxicity<\/h6>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-d838d1d elementor-widget elementor-widget-text-editor\" data-id=\"d838d1d\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><span style=\"color: #0d344a;\">No drug-related adverse reactions recorded during clinical trials &#8211; no brain swelling, epilepsy and wound-healing effects.<\/span><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3c50f13 elementor-widget elementor-widget-heading\" data-id=\"3c50f13\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h6 class=\"elementor-heading-title elementor-size-default\">\u25a0 Local Drug Delivery<\/h6>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-29065b0 elementor-widget elementor-widget-text-editor\" data-id=\"29065b0\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><span style=\"color: #0d344a;\">After implantation, the tablets will slowly decompose and release small-molecule targeted drugs directly into the tumor, so that sufficient drug concentration can be achieved locally in the lesion.<\/span><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-6600269 elementor-widget elementor-widget-heading\" data-id=\"6600269\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h6 class=\"elementor-heading-title elementor-size-default\">\u25a0 Multiple Targeting Effects\n<\/h6>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f76a4f2 elementor-widget elementor-widget-text-editor\" data-id=\"f76a4f2\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><span style=\"color: #0d344a;\">Small-molecule targeted drugs in-situ weakens the cancer, makes it highly vulnerable, less resistant, and easy to kill by the combination of additional therapies.<\/span><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-9313528 elementor-widget elementor-widget-heading\" data-id=\"9313528\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h6 class=\"elementor-heading-title elementor-size-default\">\u25a0 Improve Immune Activity\n<\/h6>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4e8e2aa elementor-widget elementor-widget-text-editor\" data-id=\"4e8e2aa\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><span style=\"color: #0d344a;\">Inhibiting tumor cell PD-L1, and activating immune system to kill tumor, thus reverses the immunosuppressive environment typically associated with traditional therapy.<\/span><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-dad1447 elementor-widget elementor-widget-spacer\" data-id=\"dad1447\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ea3dcc6 elementor-widget elementor-widget-heading\" data-id=\"ea3dcc6\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-medium\">How Cerebraca\u00ae Wafer Compares\nto Conventional Treatments of Recurrent GBM<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-07e1ecc elementor-widget elementor-widget-image\" data-id=\"07e1ecc\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"800\" height=\"450\" src=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/CW-Better-than-1024x576.png\" class=\"attachment-large size-large wp-image-1823\" alt=\"\" srcset=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/CW-Better-than-1024x576.png 1024w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/CW-Better-than-300x169.png 300w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/CW-Better-than-768x432.png 768w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/CW-Better-than.png 1366w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-365908f elementor-widget elementor-widget-heading\" data-id=\"365908f\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-medium\">Market Share (Forecast)<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-43c82b8 elementor-widget elementor-widget-image\" data-id=\"43c82b8\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"800\" height=\"450\" src=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/CW-Market-1024x576.png\" class=\"attachment-large size-large wp-image-1824\" alt=\"\" srcset=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/CW-Market-1024x576.png 1024w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/CW-Market-300x169.png 300w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/CW-Market-768x432.png 768w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/CW-Market.png 1366w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3303945 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"3303945\" data-element_type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3295771 elementor-widget elementor-widget-heading\" data-id=\"3295771\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-medium\">Key Active Ingredients<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-89dbcae elementor-widget elementor-widget-spacer\" data-id=\"89dbcae\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-9249776 elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"9249776\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-inner-column elementor-element elementor-element-5ae426f\" data-id=\"5ae426f\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-7dd4c62 elementor-widget elementor-widget-image\" data-id=\"7dd4c62\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" src=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/elementor\/thumbs\/api-1-rk8ghnl9zwk7hkb7pov43b6cbqpbgfg9yp79jlvfsg.png\" title=\"api-1\" alt=\"EF-API-001\" loading=\"lazy\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-66 elementor-inner-column elementor-element elementor-element-344940f\" data-id=\"344940f\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-d3a4ffd elementor-widget elementor-widget-heading\" data-id=\"d3a4ffd\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h6 class=\"elementor-heading-title elementor-size-default\">Active Pharmaceutical Ingredient (API): EF-API-001<\/h6>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1761748 elementor-widget elementor-widget-text-editor\" data-id=\"1761748\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<ul><li><span style=\"color: #0d344a;\">Small molecule<\/span><\/li><li><span style=\"color: #0d344a;\">Low toxicity: Rat LD50 = 1,850 mg\/kg<\/span><\/li><li><span style=\"color: #0d344a;\">PIC\/S GMP product<\/span><\/li><\/ul>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<div class=\"elementor-element elementor-element-aa6003f elementor-widget elementor-widget-text-editor\" data-id=\"aa6003f\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><span style=\"color: #ffffff;\"><b>EF-API-001<\/b> is a small molecule, discovered from natural product researches and synthesized and manufactured through strict GMP processes and controls. EF-API-001 revealed excellent safety profiles and is an exciting discovery of multiple disease treatment capabilities.<\/span><\/p><p><span style=\"color: #ffffff;\">KEY anti-cancer effects of EF-API-001: inhibiting tumor growth, inhibiting stemness, inhibiting chemo drug resistance, and immune response stimulation.<\/span><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-8bca7e2 elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"8bca7e2\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-inner-column elementor-element elementor-element-f2af6a7\" data-id=\"f2af6a7\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-bdeb418 elementor-widget elementor-widget-image\" data-id=\"bdeb418\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" src=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/elementor\/thumbs\/exp-1-rk8gflc0zzqk0db2rarl4bwxeavbkc9hchnwmqxjg0.png\" title=\"exp-1\" alt=\"exp-1\" loading=\"lazy\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-66 elementor-inner-column elementor-element elementor-element-fcf3596\" data-id=\"fcf3596\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-7414786 elementor-widget elementor-widget-heading\" data-id=\"7414786\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h6 class=\"elementor-heading-title elementor-size-default\">Excipient<\/h6>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-535667b elementor-widget elementor-widget-text-editor\" data-id=\"535667b\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<ul><li><span style=\"color: #0d344a;\">FDA approved, bio-degradable material<\/span><\/li><li><span style=\"color: #0d344a;\">Excellent bio-compatibility<\/span><\/li><li><span style=\"color: #0d344a;\">PIC\/S GMP product<\/span><\/li><\/ul>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<div class=\"elementor-element elementor-element-c17785a elementor-widget elementor-widget-spacer\" data-id=\"c17785a\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-37f027b elementor-widget elementor-widget-heading\" data-id=\"37f027b\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-medium\">Summary of Mechanism of Action (MOA)<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-de43ccf elementor-widget elementor-widget-image\" data-id=\"de43ccf\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"800\" height=\"450\" src=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2024\/05\/Cerebraca-Wafer-Critical-Signaling-for-GBM-1024x576.png\" class=\"attachment-large size-large wp-image-8485\" alt=\"\" srcset=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2024\/05\/Cerebraca-Wafer-Critical-Signaling-for-GBM-1024x576.png 1024w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2024\/05\/Cerebraca-Wafer-Critical-Signaling-for-GBM-300x169.png 300w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2024\/05\/Cerebraca-Wafer-Critical-Signaling-for-GBM-768x432.png 768w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2024\/05\/Cerebraca-Wafer-Critical-Signaling-for-GBM.png 1366w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3a39d28 elementor-widget elementor-widget-spacer\" data-id=\"3a39d28\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-0e0a8e4 elementor-widget elementor-widget-heading\" data-id=\"0e0a8e4\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h6 class=\"elementor-heading-title elementor-size-default\">How Does Cerebraca\u00ae Wafer Inhibit Brain Tumor Recurrence and Progression?<\/h6>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ec93049 elementor-widget elementor-widget-text-editor\" data-id=\"ec93049\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><span style=\"color: #0d344a;\">After the surgical resection of a brain tumor, Cerebraca\u00ae Wafer is directly implanted at the margin of the removed GBM. It features a 30-day sustained drug release and a penetration depth of up to 5 cm, creating a high drug concentration environment for effective cancer treatment.<\/span><\/p><p><span style=\"color: #0d344a;\"><strong>Cerebraca\u00ae Wafer is a multi-functional drug that:<\/strong><\/span><\/p><ul><li><span style=\"color: #0d344a;\"><strong>Inhibits receptor tyrosine kinases (Axl-1 and EGFR), thereby preventing the proliferation of cancer cells and cancer stem cells.<\/strong><\/span><\/li><li><span style=\"color: #0d344a;\"><strong>Inhibits the Axl-mTOR pathway and activates AMPK, which increases ATP levels, thereby improving the quality of life for patients.<\/strong><\/span><\/li><li><span style=\"color: #0d344a;\"><strong>Promotes the methylation of MGMT and PD-L1 promoters, overcoming chemotherapy resistance, and transforms the tumor microenvironment from cold to hot, thereby enhancing immune activity.<\/strong><\/span><\/li><\/ul>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ca2974b elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"ca2974b\" data-element_type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-792629d elementor-widget elementor-widget-spacer\" data-id=\"792629d\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-188290c elementor-widget elementor-widget-heading\" data-id=\"188290c\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-medium\">Clinical Study Status<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-f9d0335 elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"f9d0335\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-552a9f1\" data-id=\"552a9f1\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-b551dfb elementor-widget elementor-widget-heading\" data-id=\"b551dfb\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h6 class=\"elementor-heading-title elementor-size-default\">The Results of Interstitial wafers Cerebraca in  Recurrent Gliomas by Prof. Shinn-Zong Lin in ACNS<\/h6>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-e017b40 elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"e017b40\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-fc77155\" data-id=\"fc77155\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-3b730a4 elementor-widget elementor-widget-video\" data-id=\"3b730a4\" data-element_type=\"widget\" data-settings=\"{&quot;youtube_url&quot;:&quot;https:\\\/\\\/www.youtube.com\\\/watch?v=vcl8Iasd3K0&amp;t=6s&quot;,&quot;video_type&quot;:&quot;youtube&quot;,&quot;controls&quot;:&quot;yes&quot;}\" data-widget_type=\"video.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-wrapper elementor-open-inline\">\n\t\t\t<div class=\"elementor-video\"><\/div>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-8df1c89\" data-id=\"8df1c89\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-57fe9fc elementor-widget elementor-widget-text-editor\" data-id=\"57fe9fc\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><span style=\"color: #0d344a;\"><strong>Summary<\/strong><\/span><\/p><ul><li><span style=\"color: #0d344a;\">Cerebraca\u00ae Wafer, an investigational new drug developed by Everfront Biotech Inc, has shown excellent safety and efficacy in its Phase I clinical trial for the treatment of recurrent malignant brain tumors.<\/span><\/li><li><span style=\"color: #0d344a;\">The trial involved 12 patients, and those who received the highest dose had an average survival time of more than 19 months.<\/span><\/li><li><span style=\"color: #0d344a;\">Cerebraca\u00ae Wafer is designed to clear residual malignant brain tumor cells after surgery and reduce chemoresistance with the help of TMZ.<\/span><\/li><li><span style=\"color: #0d344a;\">The current standard treatments for recurrent malignant brain tumors have limited effectiveness, and there is an urgent need for new therapies.<\/span><\/li><\/ul>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<div class=\"elementor-element elementor-element-f1e7056 elementor-widget elementor-widget-spacer\" data-id=\"f1e7056\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f6108b5 elementor-widget elementor-widget-heading\" data-id=\"f6108b5\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-medium\">Awards & Achievements<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-091c92a elementor-widget elementor-widget-text-editor\" data-id=\"091c92a\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p style=\"padding-left: 40px;\"><span style=\"color: #0d344a;\"><b>2014&nbsp; &nbsp; <\/b>National Innovation Award*<\/span><\/p>\n<p style=\"padding-left: 40px;\"><span style=\"color: #0d344a;\"><b>2015&nbsp; &nbsp; <\/b>Orphan drug Designation Granted by USFDA<\/span><\/p>\n<p style=\"padding-left: 40px;\"><span style=\"color: #0d344a;\"><b>2016&nbsp; &nbsp; <\/b>Qualified by the qualified for governmental incentives under Biotech and&nbsp;<\/span><span style=\"color: #0d344a; font-size: 14px;\">New Pharmaceutical Development Act in Taiwan<\/span><\/p>\n<p style=\"padding-left: 40px;\"><span style=\"color: #0d344a;\"><b>2016&nbsp; &nbsp; <\/b>IND application approved by USFDA and TFDA<\/span><\/p>\n<p style=\"padding-left: 40px;\"><span style=\"color: #0d344a;\"><b>2019&nbsp; &nbsp; <\/b>Taipei Biotech Awards &#8211; Innovation Award*<\/span><\/p>\n<p style=\"padding-left: 40px;\"><span style=\"color: #0d344a;\"><b>2019&nbsp; &nbsp; <\/b>Congress of Neurological Surgeons &#8211; selected late-breaking presentation with the highest score<\/span><\/p>\n<p style=\"padding-left: 40px;\"><span style=\"color: #0d344a;\"><b>2019&nbsp; &nbsp; <\/b>National Innovation Award \u2013 Excelsior Award*<\/span><\/p>\n<p style=\"padding-left: 40px;\"><span style=\"color: #0d344a;\"><b>2021&nbsp; &nbsp; <\/b>National Innovation Award \u2013 Excelsior Award*<\/span><\/p>\n<p style=\"padding-left: 40px;\"><span style=\"color: #0d344a;\"><b>2022&nbsp; &nbsp; <\/b>National Innovation Award \u2013 Clinical innovation*<\/span><\/p>\n<p style=\"padding-left: 40px;\"><span style=\"font-size: 14px; color: #0d344a;\"><b>2023<\/b>&nbsp; &nbsp; NBRP DEMODAY \u2013 Investor\u2019s Choice Award<\/span><\/p>\n<p style=\"padding-left: 40px;\"><span style=\"color: #0d344a;\">&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; *Taiwan Government Awarded<\/span><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-86067b4 elementor-widget elementor-widget-spacer\" data-id=\"86067b4\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f5dc861 elementor-widget elementor-widget-heading\" data-id=\"f5dc861\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-medium\">Patents<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5da77d4 elementor-widget elementor-widget-image\" data-id=\"5da77d4\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"800\" height=\"450\" src=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/04\/EF001-patent-1024x576.png\" class=\"attachment-large size-large wp-image-2600\" alt=\"Patent portfolio for EF-001\" srcset=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/04\/EF001-patent-1024x576.png 1024w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/04\/EF001-patent-300x169.png 300w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/04\/EF001-patent-768x432.png 768w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/04\/EF001-patent.png 1366w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-d56feba elementor-widget elementor-widget-spacer\" data-id=\"d56feba\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f270ce2 elementor-widget elementor-widget-heading\" data-id=\"f270ce2\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-medium\">Publications<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ade57ca elementor-icon-list--layout-traditional elementor-list-item-link-full_width elementor-widget elementor-widget-icon-list\" data-id=\"ade57ca\" data-element_type=\"widget\" data-widget_type=\"icon-list.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<link rel=\"stylesheet\" href=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/plugins\/elementor\/assets\/css\/widget-icon-list.min.css\">\t\t<ul class=\"elementor-icon-list-items\">\n\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/doi.org\/10.3390\/cancers14041051\" target=\"_blank\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<i aria-hidden=\"true\" class=\"far fa-newspaper\"><\/i>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">2022 | Interstitial Control-Released Polymer Carrying a Targeting Small-Molecule Drug Reduces PD-L1 and MGMT Expression in Recurrent High-Grade Gliomas with TMZ Resistance<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/doi.org\/10.1097\/cad.0000000000001275\" target=\"_blank\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<i aria-hidden=\"true\" class=\"far fa-newspaper\"><\/i>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">2022 | Biodegradable Controlled-release Polymer Containing Butylidenephthalide to Treat a Recurrent Cervical Spine Glioblastoma with Promising Result: a Compassionate Trial Report<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/doi.org\/10.1155\/2022\/3236058\" target=\"_blank\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<i aria-hidden=\"true\" class=\"far fa-newspaper\"><\/i>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">2022 | Targeting the Axl and mTOR Pathway Synergizes Immunotherapy and Chemotherapy to Butylidenephthalide in a Recurrent GBM<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/doi.org\/10.3390\/ijms19041115\" target=\"_blank\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<i aria-hidden=\"true\" class=\"far fa-newspaper\"><\/i>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">2018 | Migration\/Invasion of Malignant Gliomas and Implications for Therapeutic Treatment<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/doi.org\/10.3390\/ijms18020372\" target=\"_blank\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<i aria-hidden=\"true\" class=\"far fa-newspaper\"><\/i>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">2017 | n-Butylidenephthalide Regulated Tumor Stem Cell Genes EZH2\/AXL and Reduced Its Migration and Invasion in Glioblastoma<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/doi.org\/10.1038\/onc.2015.277\" target=\"_blank\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<i aria-hidden=\"true\" class=\"far fa-newspaper\"><\/i>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">2015 | Biodegradable Interstitial Release Polymer Loading a Novel Small Molecule Targeting Axl Receptor Tyrosine Kinase and Reducing Brain Tumour Migration and Invasion<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24464249\/\" target=\"_blank\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<i aria-hidden=\"true\" class=\"far fa-newspaper\"><\/i>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">2014 | Brain tumor senescence might be mediated by downregulation of S-phase kinase-associated protein 2 via butylidenephthalide leading to decreased cell viability<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24319475\/\" target=\"_blank\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<i aria-hidden=\"true\" class=\"far fa-newspaper\"><\/i>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">2013 | The Methanol Extract of Angelica sinensis Induces Cell Apoptosis and Suppresses Tumor Growth in Human Malignant Brain Tumors<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.davidpublisher.com\/index.php\/Home\/Article\/index?id=770.html\" target=\"_blank\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<i aria-hidden=\"true\" class=\"far fa-newspaper\"><\/i>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">2013 | (Z)-Butylidenephthalide   restores   Temozolomide   sensitivity   to   Temozolomide-resistant malignant  glioma  cells  by  downregulating  expression  of  the  DNA  repair enzyme MGMT. <\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/doi.org\/10.1002\/jso.21809\" target=\"_blank\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<i aria-hidden=\"true\" class=\"far fa-newspaper\"><\/i>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">2011 | Overexpression of the Orphan Receptor Nur77 and Its Translocation Induced by PCH4 May Inhibit Malignant Glioma Cell Growth and Induce Cell Apoptosis<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/doi.org\/10.1093\/neuonc\/nor021\" target=\"_blank\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<i aria-hidden=\"true\" class=\"far fa-newspaper\"><\/i>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">2011 | Local Interstitial Delivery of z-Butylidenephthalide by Polymer Wafers against Malignant Human Gliomas<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/link.springer.com\/article\/10.1245\/s10434-011-1644-0\" target=\"_blank\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<i aria-hidden=\"true\" class=\"far fa-newspaper\"><\/i>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">2011 | Butylidenephthalide suppresses human telomerase reverse transcriptase (TERT) in human glioblastomas<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/20043672\/\" target=\"_blank\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<i aria-hidden=\"true\" class=\"far fa-newspaper\"><\/i>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">2010 | Extended O6-methylguanine methyltransferase promoter hypermethylation following n-butylidenephthalide combined with 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) on inhibition of human hepatocellular carcinoma cell growth<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/doi.org\/10.1111\/j.1471-4159.2008.05432.x\" target=\"_blank\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<i aria-hidden=\"true\" class=\"far fa-newspaper\"><\/i>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">2008 | Orphan Nuclear Receptor, Nurr-77 was a Possible Target Gene of Butylidenephthalide Chemotherapy on Glioblastoma Multiform Brain Tumor<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC1804119\/\" target=\"_blank\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<i aria-hidden=\"true\" class=\"far fa-newspaper\"><\/i>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">2006 | The natural compound n-butylidenephthalide derived from Angelica sinensis inhibits malignant brain tumor growth in vitro and in vivo<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/aacrjournals.org\/clincancerres\/article\/11\/9\/3475\/188529\/The-Antitumor-Effects-of-Angelica-sinensis-on\" target=\"_blank\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<i aria-hidden=\"true\" class=\"far fa-newspaper\"><\/i>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">2005 | The antitumor effects of Angelica sinensis on malignant brain tumors in vitro and in vivo<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/15261763\/\" target=\"_blank\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<i aria-hidden=\"true\" class=\"far fa-newspaper\"><\/i>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">2004 | Acetone extract of Angelica sinensis inhibits proliferation of human cancer cells via inducing cell cycle arrest and apoptosis<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t<\/ul>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-8ccaf3c elementor-widget elementor-widget-spacer\" data-id=\"8ccaf3c\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-366953e elementor-widget elementor-widget-heading\" data-id=\"366953e\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-medium\">Partnering And Collaboration<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-8d7958c elementor-widget elementor-widget-text-editor\" data-id=\"8d7958c\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><span style=\"color: #0d344a;\">EFB is looking for the opportunity to cooperate with international pharmaceutical companies or venture capitals.\u00a0<\/span><\/p><p><span style=\"color: #0d344a;\">Please mail us on\u00a0<\/span><a href=\"mailto:efbiotech@efbiotech.com\" target=\"_blank\" rel=\"noopener\">efbiotech@efbiotech.com<\/a><span style=\"color: #0d344a;\">\u00a0<\/span><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-9044a6e elementor-widget elementor-widget-spacer\" data-id=\"9044a6e\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-7f1a2c9 elementor-section-stretched elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"7f1a2c9\" data-element_type=\"section\" data-settings=\"{&quot;stretch_section&quot;:&quot;section-stretched&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-75eba16\" data-id=\"75eba16\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-c9d062e elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"c9d062e\" data-element_type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-e79b67d elementor-widget elementor-widget-heading\" data-id=\"e79b67d\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Development Pipeline<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-cde7325 elementor-section-full_width elementor-section-stretched elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"cde7325\" data-element_type=\"section\" data-settings=\"{&quot;stretch_section&quot;:&quot;section-stretched&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-narrow\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-2746fdd\" data-id=\"2746fdd\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-cd0f1c4 elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"cd0f1c4\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-a3b5f69\" data-id=\"a3b5f69\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-b22fcdb elementor-widget elementor-widget-image\" data-id=\"b22fcdb\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"400\" height=\"400\" src=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/pipeline-1.png\" class=\"attachment-large size-large wp-image-1709\" alt=\"Pepline - EF-001\" srcset=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/pipeline-1.png 400w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/pipeline-1-300x300.png 300w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/pipeline-1-150x150.png 150w\" sizes=\"(max-width: 400px) 100vw, 400px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-41b84aa elementor-align-center e-transform e-transform elementor-widget elementor-widget-button\" data-id=\"41b84aa\" data-element_type=\"widget\" data-settings=\"{&quot;_transform_scale_effect&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:1.03,&quot;sizes&quot;:[]},&quot;_transform_scaleX_effect_hover&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:1.1,&quot;sizes&quot;:[]},&quot;_transform_scaleY_effect_hover&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:1.1,&quot;sizes&quot;:[]},&quot;_transform_scale_effect_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_scale_effect_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_scaleX_effect_hover_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_scaleX_effect_hover_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_scaleY_effect_hover_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_scaleY_effect_hover_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t<a href=\"https:\/\/www.efbiotech.com\/wordpress\/?page_id=1778\" class=\"elementor-button-link elementor-button elementor-size-sm\" role=\"button\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-text\">EF-001<\/span>\n\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-da9c6e5\" data-id=\"da9c6e5\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-f09f18d elementor-widget elementor-widget-image\" data-id=\"f09f18d\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"400\" height=\"400\" src=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/pepline-2.png\" class=\"attachment-large size-large wp-image-1710\" alt=\"Pepline - EF-009\" srcset=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/pepline-2.png 400w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/pepline-2-300x300.png 300w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/pepline-2-150x150.png 150w\" sizes=\"(max-width: 400px) 100vw, 400px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ed5bcf8 elementor-align-center e-transform e-transform elementor-widget elementor-widget-button\" data-id=\"ed5bcf8\" data-element_type=\"widget\" data-settings=\"{&quot;_transform_scale_effect&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:1.03,&quot;sizes&quot;:[]},&quot;_transform_scaleX_effect_hover&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:1.1,&quot;sizes&quot;:[]},&quot;_transform_scaleY_effect_hover&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:1.1,&quot;sizes&quot;:[]},&quot;_transform_scale_effect_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_scale_effect_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_scaleX_effect_hover_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_scaleX_effect_hover_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_scaleY_effect_hover_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_scaleY_effect_hover_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t<a href=\"https:\/\/www.efbiotech.com\/wordpress\/?page_id=1870\" class=\"elementor-button-link elementor-button elementor-size-sm\" role=\"button\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-text\">EF-009<\/span>\n\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-e1181df\" data-id=\"e1181df\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-1797643 elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"1797643\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-6d65b93\" data-id=\"6d65b93\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-635a443 elementor-widget elementor-widget-image\" data-id=\"635a443\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"400\" height=\"400\" src=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/pepline-3.png\" class=\"attachment-large size-large wp-image-1711\" alt=\"Pepline - HK-001\" srcset=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/pepline-3.png 400w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/pepline-3-300x300.png 300w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/pepline-3-150x150.png 150w\" sizes=\"(max-width: 400px) 100vw, 400px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-cc7a6d8 elementor-align-center e-transform e-transform elementor-widget elementor-widget-button\" data-id=\"cc7a6d8\" data-element_type=\"widget\" data-settings=\"{&quot;_transform_scale_effect&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:1.03,&quot;sizes&quot;:[]},&quot;_transform_scaleX_effect_hover&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:1.1,&quot;sizes&quot;:[]},&quot;_transform_scaleY_effect_hover&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:1.1,&quot;sizes&quot;:[]},&quot;_transform_scale_effect_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_scale_effect_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_scaleX_effect_hover_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_scaleX_effect_hover_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_scaleY_effect_hover_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_scaleY_effect_hover_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t<a href=\"https:\/\/www.efbiotech.com\/wordpress\/?page_id=3417\" class=\"elementor-button-link elementor-button elementor-size-sm\" role=\"button\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-text\">HK-001<\/span>\n\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-097b854\" data-id=\"097b854\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-8fce849 elementor-widget elementor-widget-image\" data-id=\"8fce849\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"400\" height=\"400\" src=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/Pepline-4-1.png\" class=\"attachment-large size-large wp-image-1713\" alt=\"Pepline - EF-031\" srcset=\"https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/Pepline-4-1.png 400w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/Pepline-4-1-300x300.png 300w, https:\/\/www.efbiotech.com\/wordpress\/wp-content\/uploads\/2023\/03\/Pepline-4-1-150x150.png 150w\" sizes=\"(max-width: 400px) 100vw, 400px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5308cfa elementor-align-center e-transform e-transform elementor-widget elementor-widget-button\" data-id=\"5308cfa\" data-element_type=\"widget\" data-settings=\"{&quot;_transform_scale_effect&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:1.03,&quot;sizes&quot;:[]},&quot;_transform_scaleX_effect_hover&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:1.1,&quot;sizes&quot;:[]},&quot;_transform_scaleY_effect_hover&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:1.1,&quot;sizes&quot;:[]},&quot;_transform_scale_effect_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_scale_effect_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_scaleX_effect_hover_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_scaleX_effect_hover_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_scaleY_effect_hover_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_scaleY_effect_hover_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t<a href=\"https:\/\/www.efbiotech.com\/wordpress\/?page_id=5401\" class=\"elementor-button-link elementor-button elementor-size-sm\" role=\"button\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-text\">EF-031<\/span>\n\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Cerebraca\u00ae Wafer Bra<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_sitemap_exclude":false,"_sitemap_priority":"","_sitemap_frequency":"","footnotes":""},"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.efbiotech.com\/wordpress\/index.php?rest_route=\/wp\/v2\/pages\/1778"}],"collection":[{"href":"https:\/\/www.efbiotech.com\/wordpress\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.efbiotech.com\/wordpress\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.efbiotech.com\/wordpress\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.efbiotech.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1778"}],"version-history":[{"count":10,"href":"https:\/\/www.efbiotech.com\/wordpress\/index.php?rest_route=\/wp\/v2\/pages\/1778\/revisions"}],"predecessor-version":[{"id":9852,"href":"https:\/\/www.efbiotech.com\/wordpress\/index.php?rest_route=\/wp\/v2\/pages\/1778\/revisions\/9852"}],"wp:attachment":[{"href":"https:\/\/www.efbiotech.com\/wordpress\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1778"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}